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Procedure

Digital nerve procedure for Pain (PAPDAP Trial)

N/A

Waitlist Available

Led By Scott N Loewenstein, MD

Research Sponsored by Indiana University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up tinel's sign at 3 months; tinel's sign at 6 months

Awards & highlights

PAPDAP Trial Summary

This trial will compare three treatments for nerve pain after finger amputation: targeted muscle reinnervation (TMR), regenerative peripheral nerve interfaces (RPNI), and standard traction neurectomy (TN).

Eligible Conditions

Pain
Neuroma
Amputation

PAPDAP Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ tinel's sign at 3 months; tinel's sign at 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~tinel's sign at 3 months; tinel's sign at 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and tinel's sign at 3 months; tinel's sign at 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

bMHQ

Secondary outcome measures

Grip strength

NPS

Other outcome measures

Tinel's sign

PAPDAP Trial Design

3Treatment groups

Experimental Treatment

Active Control

Group I: Targeted Muscle ReinnervationExperimental Treatment1 Intervention

Targeted Muscle Reinnervation - of digital sensory nerves at the time of amputation

Group II: Regenerative Peripheral Nerve InterfaceExperimental Treatment1 Intervention

Regenerative Peripheral Nerve Interface - of digital sensory nerves at the time of amputation

Group III: Traction NeurectomyActive Control1 Intervention

Traction neurectomy - of digital sensory nerves at the time of amputation.

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Find a Location

Who is running the clinical trial?

Indiana UniversityLead Sponsor

980 Previous Clinical Trials

983,122 Total Patients Enrolled

6 Trials studying Pain

1,770 Patients Enrolled for Pain

American Society for Surgery of the HandOTHER

10 Previous Clinical Trials

1,042 Total Patients Enrolled

Scott N Loewenstein, MDPrincipal InvestigatorIndiana University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are currently signed up for this experiment?

"Affirmative. Clinicaltrials.gov confirms that this medical research, which was published on March 1st 2020, is actively recruiting subjects. A total of 39 volunteers need to be enrolled from a single testing site."

Answered by AI

Are there any available openings for participants in this clinical trial?

"Affirmative. Data hosted on clinicaltrials.gov attests to the fact that this trial, which was initially posted on March 1st 2020, is currently recruiting patients. Approximately 39 individuals must be sourced from a single site for participation in the study."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Pain After Proximal Digital Amputation Prevention

Joshua Adkinson 2020. "Pain After Proximal Digital Amputation Prevention". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04378062.