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Parasternal blocks for Coronary Artery Bypass Surgery

Phase 3

Waitlist Available

Research Sponsored by Jewish General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up immediately as intervention is performed

Awards & highlights

Study Summary

This trial will test how well parasternal blocks with local anesthetic drugs work to relieve pain after CABG surgery.

Who is the study for?

This trial is for patients scheduled for elective or urgent coronary artery bypass surgery who can give consent. It's not suitable for those with regular opioid use or chronic pain history.Check my eligibility

What is being tested?

The study tests the effectiveness of parasternal blocks, a type of regional anesthesia, in managing post-surgery pain compared to standard care after coronary artery bypass grafting.See study design

What are the potential side effects?

Parasternal blocks may cause side effects like localized discomfort, potential nerve damage, infection at the injection site, and inadequate pain relief requiring additional analgesics.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ from icu arrival until first ambulation (approximately first 72 hours postoperatively)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~from icu arrival until first ambulation (approximately first 72 hours postoperatively)

This trial's timeline: 3 weeks for screening, Varies for treatment, and from icu arrival until first ambulation (approximately first 72 hours postoperatively) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Pain with inspirometry at 24 hours after surgery

Secondary outcome measures

Ambulation

Amount of rescue analgesia administered

Hospital Length of Stay

+7 more

Other outcome measures

Incidence of a pneumothorax

Incidence of bradycardia

Incidence of hyperglycemia

+6 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Intervention groupExperimental Treatment1 Intervention

Patients will receive bilateral parasternal blocks at the end of cardiac surgery.

Group II: Control groupPlacebo Group1 Intervention

Patients will receive all standard care as per the hospital protocols.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Jewish General HospitalLead Sponsor

137 Previous Clinical Trials

271,984 Total Patients Enrolled

Media Library

Parasternal blocks Clinical Trial Eligibility Overview. Trial Name: NCT05191745 — Phase 3

Coronary Artery Bypass Surgery Research Study Groups: Intervention group, Control group

Coronary Artery Bypass Surgery Clinical Trial 2023: Parasternal blocks Highlights & Side Effects. Trial Name: NCT05191745 — Phase 3

Parasternal blocks 2023 Treatment Timeline for Medical Study. Trial Name: NCT05191745 — Phase 3

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many guinea pigs are currently testing this new drug?

"The information available on clinicaltrials.gov verifies that this study is currently looking for patients to enroll. The trial was originally posted on January 26th, 2022 and updated most recently on July 27th, 2022. 1 site is recruiting a total of 60 participants."

Answered by AI

Are we still looking for patients to participate in this experiment?

"Yes, this study is currently enrolling patients. Information on clinicaltrials.gov reveals that the trial was first posted on January 26th, 2022 and last updated on July 27th, 2022."

Answered by AI

Is there a potential for long-term harm with Parasternal blocks?

"Given that this is a Phase 3 trial with efficacy data and multiple rounds of safety data, our team at Power gives Parasternal blocks a score of 3 for safety."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Long-acting Parasternal Blocks for Analgesia After Cardiac Surgery

Matthew Cameron 2022. "Long-acting Parasternal Blocks for Analgesia After Cardiac Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05191745.