Lupus Clinical Trials 2022

Lupus studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect lupus clinical trial in 2022.

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Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the most common causes of death for lupus patients?

A study from 1995 found that the most common cause of death for lupus patients is systemic lupus erythematosus (SLE), which occurred in 49 of the 134 patients with a determined cause of death (34%). This was followed by infection (32 patients, or 22%), cardiovascular disease (23 patients, or 16%), cerebrovascular disease (8 patients, or 6%), and cancer (8 patients, or 6%). If you are looking to join a lupus clinical trial, Power can help you search recent trials by condition, treatment, or location.

Is lupus a dying disease?

With close observation and treatment, 80 to 90% of lupus patients are able to live a normal life span. While modern science has not yet found a cure for lupus, and it is possible to die from the disease, it is not fatal for most people living with the condition today. You can find the most recent lupus clinical trials by using Power, which allows you to search trials tailored to your condition, location, and ideal treatment.

What are the 4 types of lupus?

The 4 major types of lupus are systemic lupus erythematosus (SLE), lupus of the skin, drug-induced lupus erythematosus, and neonatal lupus erythematosus. SLE is the most common form of lupus and affects organs including the skin, joints, and kidneys. Lupus of the skin sometimes requires a skin biopsy to diagnose, and drug-induced lupus erythematosus is separate from SLE and is caused by taking certain prescription drugs. Finally, neonatal lupus is rare and affects the babies of women who have certain antibodies. Power makes it easy to find lupus clinical trials tailored to your condition, treatment, or location.

What does lupus joint pain feel like?

Lupus can cause inflammatory arthritis, which makes your joints hurt or feel stiff, tender, warm, and swollen. Arthritis caused by lupus most often affects joints like the fingers, wrists, knees, elbows, ankles, and toes. To find active lupus clinical trials in your area, you can use Power to search by condition, treatment, or location.

Is skin lupus the same as lupus?

While cutaneous (skin) lupus is sometimes diagnosed in people with SLE, people can develop cutaneous lupus without ever being diagnosed with SLE. Like SLE, cutaneous lupus is caused by an autoimmune response where the body attacks its own tissues and organs. However, in cutaneous lupus the immune system specifically targets skin cells, causing red, scaly rashes or sores that either burn or itch. If you are looking to join a lupus clinical trial, Power can help you search recent trials by condition, treatment, or location.

Is chicken good for lupus?

Despite claims on the Internet, books, and other publications, there is no special diet for lupus. Those living with lupus should try to eat a well-balanced, nutritious, and varied diet with plenty of fruits, vegetables, whole grains, and moderate amounts of meat and fish. You can find the most recent lupus clinical trials by using Power, which allows you to search trials tailored to your condition, location, and ideal treatment.

Can lupus be managed without medication?

Some people with lupus have tried alternatives to medication such as creams, ointments, fish oil, supplements, homeopathy or seeing a chiropractor to treat their lupus. While some find that such treatments help them, there have been no research studies that show any benefits to these types of treatments. Power makes it easy to find lupus clinical trials tailored to your condition, treatment, or location.

Can lupus make you gain weight?

Many people with lupus treat their condition with steroids, which has the potential to cause weight gain. A 2011 study found that women with lupus are affected by obesity at a lower BMI (26.8 or higher) than the general population). Women who are diagnosed with both lupus and obesity are more likely to suffer from disability, less likely to be employed, and more likely to have limitations in their daily lives than women who are not obese. To find active lupus clinical trials in your area, you can use Power to search by condition, treatment, or location.

What’s the best medication for lupus?

Medications most commonly used to treat lupus include non-steroidal anti-inflammatory drugs (NSAIDs) such as naproxen (Aleve) and ibuprofen (Advil), antimalarial drugs such as hydroxychloroquine (Plaquenil), and corticosteroids such as Prednisone. If you are looking to join a lupus clinical trial, Power can help you search recent trials by condition, treatment, or location.

Why can’t they cure lupus?

The main reason why a cure for lupus has proven difficult is that lupus is a complex disease with a number of features that make discovering new therapies difficult. This complexity has limited the insights into the pathogenesis of the disease, as patients often react to medicines in unusual ways and lack reliable biomarkers. Clinical trials help researchers understand more about lupus. You can find the most recent lupus clinical trials by using Power, which allows you to search trials tailored to your condition, location, and ideal treatment.

Are migraines common with lupus?

About 20% of lupus patients experience migraine-like headaches. However, these migraine-like headaches are different from "lupus headaches," which are caused by active lupus and require a lumbar puncture (spinal tap) or blood vessel study (MRA or CT-angiogram) to diagnose. Non-lupus migraine headaches can be treated by using a migraine prevention diet, but if this is insufficient there are medications such as nortriptyline that can be used instead. Power makes it easy to find lupus clinical trials tailored to your condition, treatment, or location.

Can lupus be left untreated?

If lupus is left untreated, you risk developing life-threatening problems such as a heart attack or stroke. Many cases of lupus do not cause noticeable symptoms, but this does not mean the condition is not dangerous. To find active lupus clinical trials in your area, you can use Power to search by condition, treatment, or location.

Can lupus go into permanent remission?

A 2016 study found that 14.5% of the lupus patients studied achieved a complete remission for 3 years. However, flare-ups were still possible beyond 10 years of remission, so long-term follow-ups for patients with SLE are still mandatory. If you are looking to join a lupus clinical trial, Power can help you search recent trials by condition, treatment, or location.

Can lupus change your appearance?

Those with cutaneous lupus erythematosus can develop rashes, sores, or lesions on sun-exposed areas such as the face, neck, ears, arms, and legs. Skin rashes and lesions caused by lupus can be treated by a dermatologist. You can find the most recent lupus clinical trials by using Power, which allows you to search trials tailored to your condition, location, and ideal treatment.

What other diseases can mimic lupus?

While lupus usually occurs alone, some people with the disease experience symptoms typical of other connective tissue diseases. These cases are known to "overlap" with lupus and include autoimmune thyroid disease, celiac disease, rheumatoid arthritis, polymyositis, scleroderma, and Sjögren's syndrome. Power makes it easy to find lupus clinical trials tailored to your condition, treatment, or location.

Does lupus make you pee a lot?

Frothy or frequent urination is a symptom of lupus nephritis, which is a type of lupus that attacks the kidneys. About 30-50% of people diagnosed with SLE develop kidney disease or lupus nephritis. Other symptoms of lupus nephritis include swelling of the feet, legs, and eyes, blood in the urine, and high blood pressure. To find active lupus clinical trials in your area, you can use Power to search by condition, treatment, or location.

Why is melatonin bad for lupus?

A 2013 study involving female patients with SLE found that melatonin concentrations decreased in patients with lupus. These decreased melatonin levels could be related to the chronic autoimmune process or the immunosuppressive treatments offered to those with lupus. If you are looking to join a lupus clinical trial, Power can help you search recent trials by condition, treatment, or location.

Is magnesium good for lupus?

There is little scientific evidence that magnesium supplementation is beneficial for people with autoimmune conditions such as lupus. However, one study involving patients with SLE recommended that magnesium levels be checked to make sure that inflammation was not due to low magnesium, rather than the autoimmune condition. You can find the most recent lupus clinical trials by using Power, which allows you to search trials tailored to your condition, location, and ideal treatment.

Does lupus affect eyesight?

Some people with lupus develop retinal vasculitis, which is a condition that limits the supply of blood to the retina. This can have a significant effect on vision, as the eye attempts to repair itself and creates new blood vessels in areas of the eye that impair vision. Power makes it easy to find lupus clinical trials tailored to your condition, treatment, or location.

Is fasting good for lupus?

A study from 2012 found that fasting is beneficial in preventing and minimizing the symptoms of autoimmune diseases such as SLE. While the reasons for this effect are not well understood, fasting is known to reduce levels of leptin, which is an adipokine with pro-inflammatory effects. To find active lupus clinical trials in your area, you can use Power to search by condition, treatment, or location.