Your session is about to expire
← Back to Search
Obinutuzumab for Lupus (ALLEGORY Trial)
ALLEGORY Trial Summary
This trial will compare the effects of a new drug, obinutuzumab, to a placebo in people with active SLE. The trial will be double-blind, meaning neither the participants nor the researchers will know who is receiving the real drug or the placebo.
ALLEGORY Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowALLEGORY Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2019 Phase 3 trial • 229 Patients • NCT02264574ALLEGORY Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- My lupus is highly active, with a SLEDAI score of 8 or more and a PGA score of 1 or more.I am currently taking medication for lupus at a stable dose.I haven't taken specific immune therapies or certain medications in the months before my screening.I do not have any severe illnesses that would stop me from joining the study.I have been diagnosed with lupus for at least 12 weeks.I do not have any current infections or recent serious infections.My lupus is very active, affecting multiple organs with high scores on health assessments.I have kidney problems due to lupus.I cannot tolerate or am advised against the study's treatments.
- Group 1: Obinutuzumab
- Group 2: Placebo
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How can I sign up for this clinical test?
"Eligible patients must have a diagnosis of libman-sacks disease and be between 18-75 years old. Currently, the medical trial is looking to enroll 200 individuals."
Is this a clinical study that only elderly people can participate in?
"This particular clinical trial only accepts patients aged 18-75. However, there are 82 other trials catering to a younger demographic and 400 for elderly patients."
How many hospitals are participating in this research project?
"This study has locations in Fullerton, Columbus, Denver, and 16 other sites."
For what purpose is Obinutuzumab most often prescribed?
"Obinutuzumab is most often used as a nephrotic syndrome treatment, but it has also been known to help patients with conditions like whiplash syndrome and ophthalmia."
Could you please tell me what other research has been done on Obinutuzumab?
"The first study into obinutuzumab was conducted in 2003 at Penn State Hershey Cancer Institute. As of now, there have been a total of 19234 completed studies with 354 trials still ongoing. Fullerton, California has a significant number of these live trials taking place."
Can people with the required qualifications join this clinical trial?
"From what is published on clinicaltrials.gov, it appears that this study is still looking for participants. The trial was first announced on October 26th 2021 and the most recent update was November 4th 2022."
What is the FDA's official stance on Obinutuzumab?
"Obinutuzumab is classified as a 3 on our Power team's safety scale. This is due to the fact that this drug has gone through Phase 3 trials, providing some evidence of efficacy and multiple rounds of data supporting safety."
Who else is applying?
What site did they apply to?
What portion of applicants met pre-screening criteria?
Share this study with friends
Copy Link
Messenger