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QL Block for Postoperative Pain in Hip Surgery

Phase < 1
Recruiting
Led By Pamela Chia, MD
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Adult subjects undergoing elective primary total hip arthroplasty
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 48 hrs post op
Awards & highlights

Study Summary

This trial will assess whether the quadratus lumborum (QL) block, a nerve block injection that numbs pain in the lower abdomen, is an effective method of pain relief for patients undergoing a total hip arthroplasty. Patients will be randomized to receive the QL nerve block with either saline or ropivacaine, and postoperative outcomes will be assessed for pain, opioid use, length of hospital stay, and patient satisfaction.

Who is the study for?
This trial is for adults having elective primary total hip arthroplasty. It's not suitable for those under 18, with allergies to local anesthetics, peripheral neuropathy, long-term opioid use, or conditions that contraindicate spinal and regional anesthesia like coagulopathy or site infections.Check my eligibility
What is being tested?
The study tests the effectiveness of Quadratus Lumborum (QL) blocks in managing pain after hip replacement surgery. Participants will be randomly assigned to receive either the QL block (active comparator) or a placebo.See study design
What are the potential side effects?
Potential side effects may include discomfort at the injection site, possible nerve damage due to needle placement, allergic reactions to the anesthetic used in QL blocks, and inadequate pain relief.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am an adult scheduled for my first total hip replacement surgery.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 48 hrs post op
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 48 hrs post op for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Pain score
Secondary outcome measures
Ambulation distance
Length of hospital stay
Opioid usage
+3 more

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Intervention GroupActive Control1 Intervention
Quadratus lumborum nerve block with 0.25% ropivacaine
Group II: Control GroupPlacebo Group1 Intervention
Quadratus lumborum nerve block with saline

Find a Location

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,530 Previous Clinical Trials
10,264,628 Total Patients Enrolled
1 Trials studying Postoperative Pain
102 Patients Enrolled for Postoperative Pain
Pamela Chia, MDPrincipal InvestigatorUniversity of California, Los Angeles
Eva Boyd, MDPrincipal InvestigatorUniversity of California, Los Angeles

Media Library

Intervention Group Clinical Trial Eligibility Overview. Trial Name: NCT05247255 — Phase < 1
Postoperative Pain Research Study Groups: Intervention Group, Control Group
Postoperative Pain Clinical Trial 2023: Intervention Group Highlights & Side Effects. Trial Name: NCT05247255 — Phase < 1
Intervention Group 2023 Treatment Timeline for Medical Study. Trial Name: NCT05247255 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the aggregate figure of people enrolled in this experiment?

"Affirmative. On clinicaltrials.gov, the available information indicates that this medical trial is currently looking for eligible patients; it was first posted on March 29th 2022 and most recently updated on April 5th 2022. The study needs to enroll 80 participants from 1 site."

Answered by AI

Is this experiment recruiting participants at present?

"Confirmed. Evidently, this clinical trial is still searching for participants and was originally posted on March 29th 2022. The last update to the listing came on April 5th of that same year and 80 individuals are needed at one site."

Answered by AI
~21 spots leftby Feb 2025