Clinical Trials in Montreal, QC

View medical research that is recruiting in Montreal, QC. Filter by phase, distance, and inclusion criteria to find cutting edge treatments & access premium care.

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This is an interventional, randomized, parallel group, treatment, Phase 3b/4, double blind, 2-arm study to assess the effect of dupilumab compared to standard of care therapy on preventing or slowing the rate of lung function decline in adult patients with uncontrolled moderate to severe a…

Prefrontal EEG (VEEGix by NeuroServo)

VEEGix is a portable device developed by NeuroServo for simplifying electroencephalograms at the bedside. It is an easy-to-use device that only requires the operator to place an adhesive strip of electrodes on the patient's forehead, connected to the device. The goal of this study is to de…

This study is evaluating whether a drug may help treat low-grade glioma.

This study is evaluating whether a combination of three drugs can be used to treat people with cancer.

This study is evaluating whether a drug called nerinetide can reduce neurological disability in people who have had a stroke and are selected for endovascular therapy without the use of a tissue plasminogen activator.

Myelodysplastic Syndrome (MDS) is a group of disorders that gradually affect the ability of a person's bone marrow (semi-liquid tissue present in many bones like backbones) to produce normal blood cells. Some people with MDS have a risk of the disease progressing to acute myeloid leukemia …

The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Relapse Free Survival (RFS) in Acute Myeloid Leukemia (AML) participants compared to Best Supportive Care (BSC) when given as maintenance therapy following allogeneic stem …

This study is evaluating whether a drug may help children with sickle cell disease.

Stereotactic Body Radiation Therapy

This study is evaluating whether a treatment can delay the progression of prostate cancer.

This study is evaluating whether a combination of two drugs may help treat small cell lung cancer.

This study is evaluating whether a combination of chemotherapy and radiation therapy is more effective than radiation therapy alone in treating patients with localized non-germinomatous germ cell tumors.

This study is evaluating whether a combination of two drugs may help treat head and neck cancer.

This study is evaluating whether an antibody-drug conjugate (ADC) which targets a receptor on cancer cells may help treat cancer.

Myelofibrosis (MF) is a bone marrow illness that affects blood-forming tissues in the body. MF disturbs the body's normal production of blood cells, causing extensive scarring in the bone marrow. This leads to severe anemia, weakness, fatigue, and an enlarged spleen. The purpose of this st…

Participants in this study will have diffuse large B-cell lymphoma (DLBCL) that has come back or not gotten better with treatment. The trial will study whether brentuximab vedotin plus two drugs works better to treat this type of cancer than the two drugs alone. Participants will be rando…

This study is evaluating whether a drug which blocks enzymes that tumor cells need for growth may help treat low-grade glioma.

This study is evaluating whether a combination of drugs may help treat cancer that has spread to the colon or rectum.

This phase II trial studies how well reduced doses of radiation therapy to the brain and spine (craniospinal) and chemotherapy work in treating patients with newly diagnosed type of brain tumor called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiati…

This study is evaluating whether a drug can improve the symptoms of familial chylomicronemia syndrome.

This study is evaluating whether a new drug called pembrolizumab can be used to treat cancer.

This study is evaluating whether a drug called durvalumab can be used safely with chemotherapy.

This study is evaluating whether a combination of a radioligand and a drug can improve the survival of patients with mHSPC.

Enfortumab vedotin (EV)

This study is evaluating whether a combination of two drugs may help treat people with a certain type of bladder cancer.

This study is evaluating whether a vaccine may help prevent infants from getting RSV.

This study is evaluating whether a combination of two drugs may help treat prostate cancer.

Inhaled Long-Acting Beta Agonist

Primary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate-or severe Chronic Obstructive Pulmonary Disease (COPD) as measured by Annualized rate of acute moderate and severe COPD exacerbation (AECOPD) Secondary Objectives: To evaluate …

Laboratory Biomarker Analysis

This study is evaluating whether a combination of chemotherapy drugs is more effective than chemotherapy alone in treating triple-negative breast cancer.

Autologous genetically modified ADP-A2M4CD8 cells

This study is evaluating whether a new type of immune therapy can help treat esophageal cancer.

Dural puncture epidural

The purpose of this prospective randomized controlled study is to compare the number of physician top-up interventions during the first stage of labour between two different neuraxial analgesia techniques : the dural puncture epidural and the standard epidural.

Elranatamab (PF-06863135)

This study is evaluating whether a drug called Elranatamab can help treat multiple myeloma.

This is a study in adults who had a heart attack (myocardial infarction). The purpose of this study is to find out whether a medicine called empagliflozin helps to lower the chances of having to go to the hospital for heart failure and whether it lowers the chances of dying from cardiovasc…

Darolutamide (Nubeqa, BAY1841788)

This study is evaluating whether the continuation of a drug which was previously shown to be effective in treating prostate cancer may be effective in treating prostate cancer.

The primary objective of the study is to evaluate the efficacy of dupilumab on the annualized rate of exacerbations in participants with Allergic Bronchopulmonary Aspergillosis (ABPA). The secondary objectives of the study are: To evaluate the effects of dupilumab on lung function in par…

This study is evaluating whether a drug may help treat lung fibrosis.

Larotrectinib Sulfate

This study is evaluating whether a drug called larotrectinib may help treat patients with certain types of cancer.

This study is evaluating whether a combination of chemotherapy and radiation therapy is more effective than chemotherapy alone in treating Ewing's sarcoma.

Th purpose of the study is to evaluate the dose response of JNJ-77242113 in efficacy at Week 16 in participants with moderate-to-severe plaque psoriasis.

This study is evaluating whether a drug called AVXS-101 can improve the health of people with spinal muscular atrophy.

This study is evaluating whether a drug may help prevent cancer from returning after surgery.

This study is evaluating whether a drug may help treat idiopathic pulmonary fibrosis.

This study is being done to see if tucatinib with trastuzumab, ramucirumab and paclitaxel works better than ramucirumab and paclitaxel to treat HER2-positive (HER2+) cancer of the gut (stomach or gastroesophageal cancer). This study will also look at what side effects happen when participa…

Hippocampal-avoidant (HA-WBRT) Radiotherapy

Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to small spots in the brain while excluding the surrounding normal brain. Whole brain radiati…

This study will evaluate the safety and tolerability profile of belantamab mafodotin when administered in combination with approved regimens of either Lenalidomide Plus Dexamethasone [Len/Dex (Arm A)] or Bortezomib Plus Dexamethasone [Bor/Dex (Arm B)] in participants with RRMM, i.e., those…

This study is evaluating whether a drug may help reduce the symptoms of Crohn's disease.

This study is evaluating whether two drugs may help reduce the risk of heart attack and stroke in patients with high cholesterol.

This study is evaluating whether a cream can help reduce itch in people with atopic dermatitis.

This study compares insulin icodec (a new insulin taken once a week) to insulin degludec (an insulin taken once daily which is already available on the market) in people with type 2 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insu…

This study is evaluating whether a drug called Mavenclad can help people with multiple sclerosis.

This study is evaluating whether a drug combination may help treat breast cancer.

This study is evaluating whether a drug may help patients with lung cancer.

This study is evaluating whether a combination of two drugs may help treat neuroendocrine tumors.

This study is evaluating whether a medication which helps reverse the effects of a blood thinner may help patients with intracranial hemorrhage.

This is a single-arm, non-randomized study of re-irradiation of diffuse intrinsic pontine glioma (DIPG)

Hyperinsulinemic/normoglycemic clamp

This study is evaluating whether a glucose/insulin clamp can prevent hyperglycaemia and reduce the inflammatory cytokine response after brain death.

Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tasks such as writing, pouring, and eating, and patients also experience associated social embarrassment. This study will assess how safe and ef…

This is a randomized, double-blind, controlled clinical trial is to evaluate the duration of efficacy of parasternal blocks with the use of local anesthetic adjuncts for analgesia after coronary artery bypass grafting surgery.

50-Hour Intervention - BC LisPram

This pilot study is a 50-hour randomized, open-label, crossover study in an inpatient setting assessing the safety, pharmacodynamics, pharmacokinetics, and closed-loop efficacy of i) BC LisPram delivery and ii) rapid insulin delivery.

This study is evaluating whether a drug combination is more effective than a drug alone.

Semaglutide is a medicine studied in patients with NASH. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. Participants will either get semaglutide or a dummy medicine - which treatment participants get is decided by chance.…

talazoparib plus enzalutamide

This study is evaluating whether a drug may help treat prostate cancer.

This study is evaluating whether a drug may help people with hepatitis B virus.

This study is evaluating whether surgery or radiation therapy is better than standard treatments for prostate cancer.

This study is evaluating whether a combination of chemotherapy, radiation therapy, and a drug which blocks DNA repair may be more effective than radiation therapy and chemotherapy alone in treating patients with newly diagnosed malignant

Dexmedetomidine 0.004 MG/ML [Precedex]

The proposed pilot study is a prospective, randomized, controlled, double-blind, single-center pilot study.The aim of this pilot project is to evaluate the feasibility of a phase III study on the use of dexmedetomidine in intrathecal in the context of elective cesarean section. The target…

This study is evaluating whether a targeted therapy or immunotherapy can be used to treat people with metastatic colorectal cancer.

This study is evaluating whether a drug which targets a specific protein on white blood cells may help treat lymphoma.

This study is evaluating whether a new type of treatment for primary mediastinal B-cell lymphoma (PMBCL) is better than standard treatment.

Platinum, investigator's choice

The purpose of this study is to compare overall survival (OS) and progression free survival (PFS) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as assessed by blinded independent central review (BICR). Hypothesis (H1): Concurrent chemoradiation therapy with pem…

This study is evaluating whether a drug may help children with type 2 diabetes.

This study is evaluating whether anticoagulation might prevent atrial fibrillation related thromboembolism in patients with chronic kidney disease.

enfortumab vedotin (EV)

This study is evaluating whether an experimental drug may help treat bladder cancer.

This study is evaluating whether a type of radiation therapy is more effective than another type of radiation therapy in treating breast cancer.

This study is evaluating whether metformin can delay the time to progression in men with low risk prostate cancer.

ARV-110 in Combination with Abiraterone

Phase 1b study to assess the combination of ARV-110 and abiraterone in patients with metastatic prostate cancer with PSA progression on abiraterone.

This study is evaluating whether a new antibiotic may help treat complicated bacteremia and native valve endocarditis.

This study is evaluating whether a combination of chemotherapy and immunotherapy may help treat biliary tract cancer.

This study is about a medicine called TAK-981 given with rituximab, used to treat adults with relapsed or refractory CD20-positive non-Hodgkin lymphoma. This study has 2 parts. The main aims of the study are: To check for side effects from treatment with TAK-981 given with rituximab. To…

The current study will compare pembrolizumab (MK-3475) plus maintenance olaparib, vs. pembrolizumab plus maintenance olaparib placebo for the treatment of squamous NSCLC. The study's 2 primary hypotheses are: Pembrolizumab plus maintenance olaparib is superior to pembrolizumab plus mainte…

This study is evaluating whether a drug may help treat cystic fibrosis.

This study is evaluating whether a drug which blocks inflammation may help treat cancer.

Apalutamide

Virginia Beach, VA

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