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Ceftriaxone for Meniscus Tears (PROPER Trial)
PROPER Trial Summary
This trial will test if a ceftriaxone injection can reduce pain and narcotic use after knee surgery for cartilage or meniscus damage.
- Meniscus Tears
- Meniscal Injury
- Cartilage Injury
PROPER Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2021 Phase 4 trial • 32 Patients • NCT04218695PROPER Trial Design
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- You have had allergic reactions to cephalosporins before.You have signs of an infection or crystal disease in your knee within the past month.You have received any treatment directly into a joint within the past six months, such as corticosteroids or biologic agents like platelet rich plasma (PRP) or stem cells.You have received a treatment called hyaluronic acid in your knee, either as a research study or a regular treatment, within the last 6 months before screening.You have taken any corticosteroid medications (injections or pills) within the past 3 months before the screening.You need to have knee arthroscopy for a procedure on your cartilage or meniscus.You have certain types of arthritis or joint inflammation related to other health conditions.You had an infection in your knee in the past.
- Group 1: Experimental
- Group 2: Placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Who does this study hope to enroll in their test groups?
"Eligible patients for this study must have a meniscus lesion and be between 18-55 years old. Currently, the trial is looking to recruit 48 individuals that fit these requirements."
Is this a clinical study that only elderly patients can participate in?
"Individuals aged 18 to 55 may be eligible for this trial, as specified by the eligibility criteria. In comparison, there are 35 trials specifically for minors and 307 trials available for patients over 65 years old."
Are there any know side-effects to taking Ceftriaxone?
"Ceftriaxone's safety is based on Phase 2 trial data, meaning that there is evidence that it does not cause harm but no indication of whether or not it is effective."
What infections does Ceftriaxone help cure?
"Ceftriaxone is commonly used to treat sepsis bacterial. This medication can also be useful in treating other conditions like complicated urinary tract infections, postoperative infection prevention, and various types of bacterial infections."
Are recruitment efforts ongoing for this experiment?
"The listed clinical trial on clinicaltrials.gov is presently recruiting patients. This specific experiment was originally made public on December 28th, 2021 with the latest update occurring January 10th, 2022."
How large is the sample size for this experiment?
"That is correct, the clinical trial indicated on clinicaltrials.gov is recruiting patients. The original posting was on December 8th, 2021 and was last updated January 10th, 2022. They are looking for a total of 48 participants between 1 site."
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