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Procedure

Knee Surgery vs Physical Therapy for Osteoarthritis

N/A

Waitlist Available

Led By Jeffrey N. Katz, MD, MS

Research Sponsored by Brigham and Women's Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Evidence of osteophyte formation or cartilage fissure, tear, or loss on a knee MRI OR plain radiographic evidence of osteophyte formation or joint space narrowing

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 60 months

Awards & highlights

Study Summary

This trial will compare surgery and physical therapy for people with a torn meniscus and knee OA.

Who is the study for?

This trial is for people with a specific knee problem where the cushioning cartilage (meniscus) is torn and they also have osteoarthritis. They must have had symptoms for at least a month, tried some treatments like meds or physical therapy, and be okay with being randomly assigned to treatment groups. People can't join if they've had previous knee surgery on the affected leg, are pregnant, have certain other joint diseases or severe arthritis needing total knee replacement.Check my eligibility

What is being tested?

The study compares two common treatments for meniscal tears in patients with osteoarthritis: one group will undergo arthroscopic partial meniscectomy followed by rehab physical therapy; another group will receive standard physical therapy without surgery. The goal is to see which approach helps more.See study design

What are the potential side effects?

Surgery may lead to risks such as infection, blood clots, pain at the incision site, and complications from anesthesia. Physical therapy could cause muscle soreness or strain. Each person's reaction to treatment can vary.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My knee scans show signs of bone spurs or cartilage damage.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 60 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~60 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 60 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

WOMAC Functional Status - Difference From Baseline

Secondary outcome measures

KOOS Pain - Difference From Baseline

KOOS Pain - Mean at 60 Months

SF-36 Physical Functional Status Scale - Difference From Baseline

+1 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: SurgicalExperimental Treatment2 Interventions

Participants will undergo arthroscopic partial menisectomy (APM) surgery and offered postoperative rehabilitative physical therapy.

Group II: NonoperativeActive Control1 Intervention

Participants will undergo standard physical therapy that will include strengthening and stretching sessions one to three times a week for 8 weeks.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Brigham and Women's HospitalLead Sponsor

1,608 Previous Clinical Trials

11,469,526 Total Patients Enrolled

16 Trials studying Osteoarthritis

29,522 Patients Enrolled for Osteoarthritis

Jeffrey N. Katz, MD, MSPrincipal InvestigatorBrigham and Women's Hospital

Media Library

Arthroscopic partial menisectomy (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT00597012 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

In how many locations is this trial being conducted?

"Currently, 7 medical institutes are overseeing this trial. These include Brigham and Women's Hospital in Boston, Rush University Medical Center in Chicago, and the Hospital for Special Surgery located in New york City; other sites round out the total number of participating locations."

Answered by AI

Are applications still being accepted for this experiment?

"According to clinicaltrials.gov, this trial has since concluded its recruitment period, having last been edited on September 13th 2022 after initially being posted in May of 2008. Nevertheless, 613 other medical studies are still actively recruiting patients for their trials."

Answered by AI