OA Clinical Trials
Here are the 6 most popular medical studies for oa
Local Anesthesia
iPACK Block for Postoperative Pain
This trial seeks to evaluate whether adding a regional nerve block (iPACK) to a standard multimodal analgesia regimen (ACB + LIA) during and after total knee arthroplasty can provide improved pain relief and shorter hospital stay.
Barbiturate
Amobarbital/Gel-One for Osteoarthritis
This trial is testing whether amobarbital can prevent post-traumatic osteoarthritis in people who have fractured their ankle joints. The study is double-blind, meaning that neither the patients nor the researchers will know who is receiving the placebo or the active treatment. The study team will assess safety and begin to evaluate efficacy of amobarbital/Gel-One in patients having sustained tibial pilon fractures. The study team will use advanced imaging-based methods we have developed to characterize how joints subjected to varying levels of fracture severity and residual elevated contact stress respond in treated and control groups.
Leukotriene Inhibitor
Montelukast for Anterior Cruciate Ligament Injury
This trial will test whether montelukast can reduce markers of inflammation and cartilage degradation in people who have undergone ACL reconstruction, specifically targeting those with additional meniscal injuries who are at greater risk of rapid cartilage degradation.
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Hip Osteoarthritis Clinical Trials
View 88 Hip Osteoarthritis medical studies.
Benzoyl Peroxide Gel for Total Hip Arthroplasty
This trial is testing how well a low-virulence bacterium, Propionibacterium (P) acnes, grows on hips. P. acnes is the same bacterium that causes acne. Information about how this bacterium affects hip surgery is currently unknown.
OA Clinical Trials
View 87 OA medical studies.
Benzoyl Peroxide Gel for Total Hip Arthroplasty
This trial is testing how well a low-virulence bacterium, Propionibacterium (P) acnes, grows on hips. P. acnes is the same bacterium that causes acne. Information about how this bacterium affects hip surgery is currently unknown.
Osteoarthritis Clinical Trials With No Placebo
View 98 osteoarthritis medical studies that do not have a placebo group.
Benzoyl Peroxide Gel for Total Hip Arthroplasty
This trial is testing how well a low-virulence bacterium, Propionibacterium (P) acnes, grows on hips. P. acnes is the same bacterium that causes acne. Information about how this bacterium affects hip surgery is currently unknown.
Corticosteroid
PRGF Supplementation for Temporomandibular Joint Osteoarthritis
This trial will compare the effectiveness of two treatments for temporomandibular joint osteoarthritis, one with a steroid and one with platelet-rich growth factor supplementation.
View More Oa Trials
See another 78 many medical studies focused on oa.
Frequently Asked Questions
Introduction to oa
What are the top hospitals conducting oa research?
When it comes to clinical trials focused on osteoarthritis (OA), several leading hospitals across the United States are spearheading innovative research efforts. In Boston, Brigham and Women's Hospital is at the forefront with four ongoing OA trials. This renowned institution is dedicated to finding solutions for this degenerative joint disease that affects millions of people worldwide. Similarly, in Seattle, the University of Washington is actively conducting four clinical trials centered around OA, focusing on understanding the causes and developing effective treatments. In Chicago, Rush University Medical Center is making strides with three active OA trials aimed at improving quality of life for individuals living with this condition.
Heading east towards New York City, we find NYU Langone Health contributing its expertise through three ongoing OA trials. With a strong focus on patient-centered care and cutting-edge research, they aim to alleviate pain and enhance mobility for individuals impacted by OA.
Lastly, in Gainesville, Florida, researchers at the University of Florida are also dedicating themselves to combatting OA through their involvement in three active clinical trials. These studies strive to unravel the underlying mechanisms behind this debilitating condition while exploring novel treatment approaches.
While these hospitals have not conducted any all-time OA trials as of yet—suggesting an area where further exploration may be needed—their commitment combined with advancements made elsewhere bring hope to those suffering from osteoarthritis. Through collaboration and continued research efforts among these esteemed institutions nationwide, breakthroughs could soon be within reach for millions affected by this prevalent joint disease
Which are the best cities for oa clinical trials?
When it comes to osteoarthritis clinical trials, several cities are leading the way in research and development. New York, with 23 active trials, focuses on interventions like Active Treatment (TG-C), Vancomycin powder, and Phase 1: Best Practices + Duloxetine + Pain coping skills. Chicago follows closely behind with 17 ongoing studies exploring treatments such as Lorecivivint and Vancomycin powder. Miami and San Antonio both have 12 active trials each, investigating options like Pentosan Polysulfate Sodium twice weekly and Lorecivivint. Lastly, Birmingham offers 11 active trials examining interventions including Reparel Knee Sleeve alongside other potential breakthroughs in osteoarthritis management. These cities provide individuals with access to cutting-edge clinical trials that aim to improve the quality of life for those living with osteoarthritis.
Which are the top treatments for oa being explored in clinical trials?
Clinical trials are actively investigating several cutting-edge treatments for osteoarthritis (OA). At the forefront of research is JAK inhibitors, which have shown promising results in reducing inflammation and slowing down disease progression. Another exciting area of exploration is stem cell therapy, with researchers exploring the potential of using mesenchymal stem cells to regenerate damaged cartilage. Additionally, growth factors like platelet-rich plasma (PRP (OA). At the forefront of research is JAK inhibitors, which have shown promising results in reducing inflammation and slowing down disease progression. Another exciting area of exploration is stem cell therapy, with researchers exploring the potential of using mesenchymal stem cells to regenerate damaged cartilage. Additionally, growth factors like platelet-rich plasma (PRP) are being studied for their ability to promote tissue repair and alleviate OA symptoms. These innovative therapies offer hope for improved management and relief from the debilitating effects of OA.
What are the most recent clinical trials for oa?
Recent clinical trials have brought promising developments in the treatment of osteoarthritis (OA). One notable trial explores the potential benefits of Celltex-AdMSCs, a Phase 2 study that investigates the use of adult mesenchymal stem cells derived from adipose tissue for OA. Additionally, ASA is being evaluated in a Phase 3 trial as a potential therapy for OA. Another trial focuses on Group A TA 40 mg and its effects on OA patients during its Phase 4 stage. Furthermore, an intervention study encompassing both Phase 1 and Phase 2 aims to assess novel approaches for managing OA symptoms. Lastly, GNSC-001 at low doses is being investigated through a Phase 1 trial to determine its efficacy in treating OA. These comprehensive investigations offer hope for improved therapeutic options in tackling this widespread condition
What oa clinical trials were recently completed?
Recently, several clinical trials have been completed, bringing us closer to advancing our understanding and treatment of osteoarthritis (OA). These trials include investigations into new therapies and interventions aimed at mitigating the impact of OA on patients' lives. While specific details may vary, these studies collectively contribute valuable insights that can potentially lead to better options for managing this degenerative joint disease.