PRP vs Corticosteroids for Basal Joint Osteoarthritis
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment for basal joint osteoarthritis?
Is it safe to use PRP and corticosteroid injections in humans?
How does the treatment of PRP compare to corticosteroids for osteoarthritis?
What is the purpose of this trial?
Single blinded PRP vs. Corticosteroid vs. Placebo (normal saline) intra-articular injection for basal joint arthritis.
Eligibility Criteria
This trial is for people with early to moderate osteoarthritis in the basal joint of the thumb. It's not suitable for those with fibromyalgia, inflammatory diseases, bone tumors, certain wrist conditions like DeQuervain's tenosynovitis recently treated or advanced arthritis as per Eaton stage 4. Pregnant or terminally ill patients and those who've had a corticosteroid injection in the past year at the affected site are also excluded.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive intra-articular injections of either PRP, corticosteroid, or placebo for basal joint arthritis
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Corticosteroid injection
- Normal Saline
- Platelet Concentrate
Corticosteroid injection is already approved in United States, European Union, Canada for the following indications:
- Allergic reactions
- Asthma
- COPD
- Rheumatoid arthritis
- Osteoarthritis
- Bursitis
- Tendonitis
- Skin conditions
- Eye conditions
- Gastrointestinal disorders
- Allergic reactions
- Asthma
- COPD
- Rheumatoid arthritis
- Osteoarthritis
- Bursitis
- Tendonitis
- Skin conditions
- Eye conditions
- Gastrointestinal disorders
- Allergic reactions
- Asthma
- COPD
- Rheumatoid arthritis
- Osteoarthritis
- Bursitis
- Tendonitis
- Skin conditions
- Eye conditions
- Gastrointestinal disorders
Find a Clinic Near You
Who Is Running the Clinical Trial?
Kettering Health Network
Lead Sponsor