Dietary Supplement
Calcium Fructoborate for Joint Discomfort
This trial tests a natural supplement called calcium fructoborate (CFB) to see if it can reduce joint pain in adults. The supplement may help by reducing inflammation in the body. Participants will take the supplement daily for a few months to measure changes in their joint discomfort and overall well-being. Calcium fructoborate (CFB) is a dietary supplement used for managing joint discomfort, leveraging the benefits of organic boron-containing molecules.
Vitamin
Vitamin D + Fish Oil for Health Improvement
This trial is studying whether taking daily dietary supplements of vitamin D3 or omega-3 fatty acids reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses.
Cannabinoid
Pure Green sublingual tablets for Pain
This trial is testing Pure Green sublingual tablets to see if they are safe and effective for reducing knee pain in people with osteoarthritis. The tablets dissolve under the tongue to quickly deliver pain-relieving ingredients.
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Trials for Osteoarthritis Patients
Stem Cell Therapy
Wharton's Jelly Injections for Knee Osteoarthritis
This trial is a small initial study that will look at the safety and feasibility of using Wharton's Jelly allograft injections in patients with knee osteoarthritis. Participants will be divided into three
Behavioural Intervention
Physical Activity Program for Dementia and Chronic Pain
"This trial aims to create an exercise program for knee osteoarthritis that is suitable for individuals with memory problems. The study consists of two parts: Part 1 involves interviews with individuals aged
Selective Serotonin and Norepinephrine Reuptake Inhibitor
Pain Medication for Knee Osteoarthritis
This trial is for people with knee osteoarthritis pain at Northwestern University. It will last about 20 weeks and involve 180 participants. Participants will be split into three groups and given either dul
Corticosteroid
Corticosteroid Injection for Osteoarthritis
This trial found that a single intra-articular injection of triamcinolone acetonide was associated with decreased cartilage breakdown products in the early stages of OA, specifically in patients with higher degrees of synovitis.
Procedure
MFAT for Knee Osteoarthritis
This trial compares the effects of injecting processed fat tissue versus traditional steroid injections in patients with mild to moderate knee osteoarthritis. The fat is taken from the patient's body, slightly processed, and then injected into the knee to help heal and reduce pain and swelling.
Trials for OA Patients
Stem Cell Therapy
Wharton's Jelly Injections for Knee Osteoarthritis
This trial is a small initial study that will look at the safety and feasibility of using Wharton's Jelly allograft injections in patients with knee osteoarthritis. Participants will be divided into three
Behavioural Intervention
Physical Activity Program for Dementia and Chronic Pain
"This trial aims to create an exercise program for knee osteoarthritis that is suitable for individuals with memory problems. The study consists of two parts: Part 1 involves interviews with individuals aged
Selective Serotonin and Norepinephrine Reuptake Inhibitor
Pain Medication for Knee Osteoarthritis
This trial is for people with knee osteoarthritis pain at Northwestern University. It will last about 20 weeks and involve 180 participants. Participants will be split into three groups and given either dul
Corticosteroid
Corticosteroid Injection for Osteoarthritis
This trial found that a single intra-articular injection of triamcinolone acetonide was associated with decreased cartilage breakdown products in the early stages of OA, specifically in patients with higher degrees of synovitis.
Procedure
MFAT for Knee Osteoarthritis
This trial compares the effects of injecting processed fat tissue versus traditional steroid injections in patients with mild to moderate knee osteoarthritis. The fat is taken from the patient's body, slightly processed, and then injected into the knee to help heal and reduce pain and swelling.
Trials With No Placebo
Stem Cell Therapy
Wharton's Jelly Injections for Knee Osteoarthritis
This trial is a small initial study that will look at the safety and feasibility of using Wharton's Jelly allograft injections in patients with knee osteoarthritis. Participants will be divided into three
Behavioural Intervention
Physical Activity Program for Dementia and Chronic Pain
"This trial aims to create an exercise program for knee osteoarthritis that is suitable for individuals with memory problems. The study consists of two parts: Part 1 involves interviews with individuals aged
Procedure
MFAT for Knee Osteoarthritis
This trial compares the effects of injecting processed fat tissue versus traditional steroid injections in patients with mild to moderate knee osteoarthritis. The fat is taken from the patient's body, slightly processed, and then injected into the knee to help heal and reduce pain and swelling.
Stem Cell Therapy
Stem Cell Transplantation + Arthroscopy for Knee Osteoarthritis
This trial is comparing two different treatments for patients with mild to moderate osteoarthritis. One treatment involves harvesting fat from the patient and transplanting stem cells from that fat, in addition to standard arthroscopic procedures. The other treatment is just the standard arthroscopic procedures without the stem cell transplant.
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Frequently Asked Questions
Introduction to knee pain
What are the top hospitals conducting knee pain research?
When it comes to finding innovative solutions for knee pain, several hospitals are leading the way with their ongoing clinical trials. Northwestern University in Chicago has two active trials focused on knee pain, demonstrating their commitment to understanding and treating this common ailment. Similarly, the Medical University of South carolina in Charleston is also actively studying knee pain through two ongoing trials. In Winter Park, Conquest Research is making strides with their two current knee pain trials as well. Additionally adding itself to this list is M D Anderson Cancer Center in Houston where they're currently conducting one trial focusing on alleviating knee pain; while Auburn University also contributes significantly by having one such experiment running at the moment.
These hospitals recognize the importance of addressing knee pain, which can significantly impact individuals' quality of life and mobility. Through these clinical trials, researchers aim to develop new treatments and interventions that may revolutionize how we manage and alleviate knee pain. By combining medical expertise with cutting-edge research techniques, these institutions contribute greatly not only towards improving treatment options but also enhancing our understanding of the mechanisms behind this widespread condition. With every study conducted at these esteemed facilities, we move closer toward a future where individuals suffering from chronic or acute knee pain can find relief and regain control over their lives
Which are the best cities for knee pain clinical trials?
When it comes to knee pain clinical trials, several cities offer notable research opportunities. Hartford, Connecticut has 3 active trials investigating Autologous Bone Grafting and other treatments. Chicago, Illinois also has 3 ongoing studies focusing on X0002, SL-1002, and additional interventions. Houston, Texas follows closely with 2 active trials exploring Group 1 (standard steroid injection), Wireless neuromodulation technology, and more. Additionally, New york City and La Mesa in California each have 2 active trials examining innovative approaches such as Dorsal Root Ganglion Stimulation and Resiniferatoxin for knee pain management. These cities contribute to the advancement of knowledge and potential treatment options for individuals suffering from knee pain.
Which are the top treatments for knee pain being explored in clinical trials?
Clinical trials are actively investigating various treatments to alleviate knee pain. Among the forefront contenders are:
- Platelet-rich plasma (PRP): A technique that uses a patient's own blood components to promote healing and reduce inflammation.
- Hyaluronic acid injections: These provide lubrication and cushioning within the knee joint, potentially relieving discomfort.
- Mesenchymal stem cells: Derived from bone marrow or adipose tissue, these cells have shown promise in promoting tissue regeneration and reducing inflammation in early studies of knee pain management. These innovative approaches hold great potential for improving the lives of individuals suffering from knee pain, with ongoing research striving towards more effective treatment options.
What are the most recent clinical trials for knee pain?
Exciting advancements in the field of knee pain management have emerged through recent clinical trials. One notable study explored the effectiveness of a SAM ultrasound device and diclofenac patch in alleviating knee pain, offering potential relief to those suffering from this common ailment. Additionally, researchers investigated the impact of various treatments such as knee osteoarthritis, SL-1002, resiniferatoxin, and 6% aqueous phenol on reducing knee pain. With these innovative trials paving the way forward for improved treatment options, individuals burdened by knee pain can anticipate promising developments on the horizon.
What knee pain clinical trials were recently completed?
Recently, several clinical trials focusing on knee pain have been successfully completed, bringing hope for those suffering from this debilitating condition. These trials include a study sponsored by Massachusetts General Hospital that investigated the effectiveness of a novel drug in alleviating knee pain. Another trial conducted by Johns Hopkins University explored the potential benefits of non-invasive treatments for knee pain management. Additionally, researchers at Stanford University recently completed a trial examining the efficacy of physical therapy interventions in reducing knee pain and improving function. These significant advancements signify progress in addressing knee pain and offer prospects for improved quality of life for patients experiencing this common issue.