Study Summary
This trial is testing a new drug for people with symptomatic knee osteoarthritis to see if it is effective, safe, and tolerable.
- Knee Osteoarthritis
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 9 Secondary · Reporting Duration: Week 2, 4, 8 and 12
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
DFV890
1 of 2
Placebo
1 of 2
Active Control
Non-Treatment Group
108 Total Participants · 2 Treatment Groups
Primary Treatment: DFV890 · Has Placebo Group · Phase 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 50 - 80 · All Participants · 7 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Georgia | 50.0% |
| Texas | 50.0% |
What site did they apply to?
| Novartis Investigative Site | 100.0% |
What portion of applicants met pre-screening criteria?
| Did not meet criteria | 33.3% |
| Met criteria | 66.7% |
Why did patients apply to this trial?
- "I have arthritis and extensive pain due to no remaining meniscus in my right knee. I have had hyaluronic gel injections for temporary relief but they are wearing off. I do not want a knee replacement yet, and I have two children under the age of 6 that I would like to remain active with."
How many prior treatments have patients received?
| 1 | 50.0% |
| 3+ | 50.0% |
How responsive is this trial?
Most responsive sites:
- Novartis Investigative Site: < 48 hours
Average response time
- < 2 Days
Typically responds via
| 100.0% | |
Frequently Asked Questions
How can I become part of this medical research?
"This clinical trial is accepting candidates between the ages of 50 and 80, who are suffering from osteoarthritis in their knee. Around 108 individuals will be selected for participation." - Anonymous Online Contributor
To what extent has recruitment expanded for this trial?
"Affirmative, clinicaltrials.gov confirms that recruitment is ongoing for this trial which was first listed on September 20th 2021. The latest update to the listing occurred November 21st 2022 and the team needs to enlist 108 patients from 8 different medical facilities." - Anonymous Online Contributor
Is this experiment accepting new participants at the moment?
"Affirmative, clinicaltrials.gov corroborates that this research trial is actively seeking patients. Originally posted on September 20th 2021, it was recently updated on November 21st 2022 and requires 108 participants from 8 distinct sites." - Anonymous Online Contributor
Has DFV890 received clearance by the Food and Drug Administration?
"While there is preliminary data suggesting the safety of DFV890, efficacy has yet to be tested. Consequently, our team at Power rated it a 2 on a scale from 1-3." - Anonymous Online Contributor
What is the number of healthcare institutions conducting this experiment?
"At present, this medical trial is being conducted in 8 different sites. These locations span from Plantation to Miami Lakes and Chicago with many other places in between. If you are looking to participate, it is best to choose the nearest centre so as not to burden yourself with excessive travel." - Anonymous Online Contributor
Is this trial available for those over the age of 40?
"This experiment is only open to individuals between 50 and 80 years of age. There are 38 trials catering to youths below 18, while 656 studies cater to the elderly population above 65." - Anonymous Online Contributor