This trial is evaluating whether Treatment will improve 1 primary outcome and 6 secondary outcomes in patients with Total Knee Arthroplasty (TKA). Measurement will happen over the course of Immediately after surgical intervention (TKA) for days 1 through 7 after surgery. Using numeric rating scale..
This trial requires 429 total participants across 3 different treatment groups
This trial involves 3 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 4 and have been shown to be safe and effective in humans.
"The most common therapy in randomized clinical trials is surgery with or without a biological or mechanical prosthesis. It seems unlikely that a biological or mechanical prosthesis will replace whole joint arthroplasty." - Anonymous Online Contributor
"Total knee arthroplasty does not invariably restore knee function to that of the unaffected limb. Although patient satisfaction is acceptable, surgeons and the broader orthopaedic community must consider other factors including the physical limitations and functional outcome of a limb, which may not be improved on TKA." - Anonymous Online Contributor
"There was a wide range in the reasons for tka, but many reasons did not appear to be related to patient age, gender, ethnicity, or type of tka used." - Anonymous Online Contributor
"For total knee and hip replacement procedures, the rates of tka are rising dramatically. The use of patient and insurance characteristics in the determination of these changes likely plays a significant role in the increase in tka. Further studies are needed to determine whether the increase in the use of tka in the United States is being due to better surgical technique, or to increased indications for tka for people who would benefit from it." - Anonymous Online Contributor
"TKA is a common operation that can be done to rehabilitate patients with knee osteoarthritis. TKA is now an important and rewarding procedure in which the results can not only last a lifetime, but be durable and functional. TKA is a safe and versatile operation that can be performed on patients of all ages. TKA would be a safe and effective measure to alleviate pain and disability in millions of people every year." - Anonymous Online Contributor
"tka is a highly effective surgical treatment with a success rate of 80-90%. Many patients have post-operative deficits because of their age, illness or concomitant injuries. Some patients also have tka after an injury.\nCurrently most clinical signs of TKA are based on the American Orthopaedic Association's (AO) Joint Committee on Standards of Clinical Radiology's (COJOS) Criteria. These criteria are defined as the five following signs:\n\n- a. Any pain in the area of the knee or swelling above and below the knee\n- b. A lump in the same area\n- c." - Anonymous Online Contributor
"TKA can be effectively and effectively performed, resulting in excellent subjective function and a stable revision rate of 11%. Patient age and gender are independent factors that may influence outcome following a revision TKA." - Anonymous Online Contributor
"Patients with lower activity levels (e.g. those in a wheelchair who have an activity limitation), those who were younger, white, and female may be candidates for clinical trials to prevent TKA recurrence or revision. Given the limitations in the data analyzed, prospective trials are needed to provide more information on which patients should or should not participate in a clinical trial of TKA." - Anonymous Online Contributor
"The current study corroborates the notion that combined meniscal and cartilage surgery is an effective treatment for most patients with OA, but the results did not reach statistical significance." - Anonymous Online Contributor
"The primary causes of TKA are pain, deformity (such as malalignment or subluxation), and poor function. Deformity and malalignment occur in about one-third to one-half of patients. The primary causes of pain are instability of the knee, and most common causes of pain are osteoarthritis, osteoarthritis of the patella, bicompartmental cartilage damage, patellar resurfacing, and acute or chronic chondritis. Degenerative changes are the most common cause of bone loss in the knee." - Anonymous Online Contributor
"The majority of patients treated for tKA were discharged home. We found few patients were discharged to rehabilitation or long-term inpatient care. This result suggested patients may not follow the expected course of treatment after tKA. Other findings include differences in patients' baseline knee function, which can be used by clinicians to counsel patients about expected outcomes and care plans for the period after tKA." - Anonymous Online Contributor
"Total knee arthroplasty can be lifesaving and durable. Most patients can expect to live 20 years or more. TKA has significant short-term complications and requires significant blood loss. Arthroscopic surgery can address a multitude of other knee problems. To minimize the risk of complications or increase the time to resolution, a multidisciplinary approach is important." - Anonymous Online Contributor