Toxicity Clinical Trials 2023

What are the top hospitals conducting toxicity research?

When it comes to clinical trials focused on toxicity, some of the top hospitals worldwide are contributing valuable research and advancements in this field. In Rochester, Minnesota, the renowned Mayo Clinic is currently undertaking three active toxicity trials. With a commitment to patient care and medical innovation, Mayo Clinic has established itself as a leader in healthcare. Moving south to Charleston, South carolina, the Medical University of South Carolina is also actively conducting three toxicity trials. This esteemed institution is known for its expertise in various medical specialties and its dedication to improving patient outcomes.

Meanwhile, in Minneapolis at the Masonic Cancer Center of the University of Minnesota, researchers are engaged in two ongoing studies addressing toxicity concerns. The center's mission extends beyond treatment protocols into groundbreaking research aimed at better understanding toxic effects associated with different interventions. Similarly driven by a strong focus on pediatric health is The Hospital for Sick Children located in Toronto; this hospital has committed itself to two current clinical trials that specifically target potential toxicities across diverse age groups.

Last but not least on our list is the University of Texas MD Anderson Cancer Center situated in Houston—a hub for cutting-edge cancer research—where scientists are currently involved in two active clinical trials centered on toxicity assessment. With their innovative approach towards personalized medicine and multidisciplinary collaboration between experts from various fields spanning oncology and pharmacology among others—they aim to redefine how we understand treatment side effects while striving tirelessly towards improving patients' quality of life.

These leading institutions collectively reflect an unwavering commitment to exploring new frontiers when it comes to studying drug-related side effects and other forms of toxicity commonly encountered during treatments or interventions across diverse populations.

Which are the best cities for toxicity clinical trials?

When it comes to toxicity clinical trials, several cities have emerged as leaders in this field of research. Toronto, Ontario leads the way with 9 active trials focused on studying interventions like reduced margin, abatacept, and PRO-ACTIVE EAT + EXERCISE. Washington, District of Columbia follows closely behind with 6 ongoing studies examining chemotherapy regimens that include ddAC, acetaminophen/APAP, and simvastatin. Boston, Massachusetts is also a prominent city for toxicity trials with 6 active studies investigating treatments such as anakinra, atorvastatin, and accelerated photon radiation therapy (XRT) group. Other noteworthy cities include Houston, Texas and Cleveland Ohio where researchers are exploring various interventions to address toxicity concerns in patients undergoing treatment for different conditions. These cities offer individuals the opportunity to participate in cutting-edge clinical trials that aim to enhance safety profiles and minimize adverse effects associated with medical interventions.

Which are the top treatments for toxicity being explored in clinical trials?

Clinical trials are actively investigating various treatments to address toxicity in patients. Some of the top contenders include:

• Daratumumab: 6 active trials, 134 all-time breast cancer trials, first listed in 2012.
• Belantamab mafodotin: 4 active trials, 26 all-time breast cancer trials, first listed in 2018.
• Lenalidomide: Currently involved in three ongoing breast cancer studies and has participated in a remarkable total of 280 clinical trials since its debut back in 2003.

These treatments show promise and signify significant progress towards managing toxicity effectively.

What are the most recent clinical trials for toxicity?

Recent clinical trials have made significant strides in addressing the issue of toxicity. One promising study focuses on a reduced elective dose combined with concurrent capecitabine/mitomycin C, aiming to minimize toxic side effects while maintaining treatment efficacy. Another trial examines high-dose ORC-13661 as a potential solution for toxicity management. Additionally, blinatumomab has shown promise in reducing adverse effects associated with certain treatments. A chemotherapy regimen inclusive of ddAC is being explored to mitigate toxicity concerns through careful drug selection and dosage optimization. Lastly, TARA-002 presents an intriguing avenue for managing toxicity-related complications. These ongoing trials hold great promise in improving patient outcomes by minimizing treatment-associated toxicities and enhancing quality of life.

What toxicity clinical trials were recently completed?

Several recent clinical trials have focused on toxicity, aiming to shed light on potential adverse effects of various treatments. These studies provide valuable insights into the safety profiles of different therapies and play a crucial role in patient care. While specific details vary depending on each trial's design, several noteworthy investigations deserve attention for their contributions in this area. Researchers completed a significant toxicity trial involving Uproleselan in October 2021, spearheaded by Washington University School of Medicine. Additionally, AgenTus Therapeutics concluded an important study examining agenT-797 toxicity levels back in January 2021. These trials highlight the commitment to understanding and managing treatment-related toxicities for improved patient outcomes while highlighting areas that warrant further investigation and refinement.