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1 for Ototoxicity

N/A
Waitlist Available
Research Sponsored by University Health Network, Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up before and after cisplatin treatment
Awards & highlights

Study Summary

Aspirin (ASA) has been shown, in an animal model, to attenuate the ototoxic properties of cisplatin. The researchers plan to investigate this in patients undergoing cisplatin chemotherapy. The researchers hypothesise that low-dose aspirin can prevent cisplatin induced ototoxicity in the clinical setting.

Eligible Conditions
  • Ototoxicity
  • Hearing Loss

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~before and after chemotherapy
This trial's timeline: 3 weeks for screening, Varies for treatment, and before and after chemotherapy for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Hearing impairment
Secondary outcome measures
Hearing impairment

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: 1Experimental Treatment1 Intervention
325mg ASA OD during course of chemotherapy
Group II: 2Placebo Group1 Intervention
placebo OD during course of chemotherapy
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Acetylsalicylic acid
FDA approved

Find a Location

Who is running the clinical trial?

University Health Network, TorontoLead Sponsor
1,473 Previous Clinical Trials
484,895 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Does Aspirin Have a Protective Role Against Chemotherapeutically Induced Ototoxicity?
2008. "Does Aspirin Have a Protective Role Against Chemotherapeutically Induced Ototoxicity?". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00578760.
All > Uti > Durlaza
~6 spots leftby Apr 2025
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