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Lisinopril for Preventing Urinary Side Effects in Prostate Cancer Radiotherapy
Study Summary
This trial will help determine the best dose of lisinopril for men with prostate cancer undergoing radiation, and whether the drug can help relieve urinary symptoms.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I've been mostly active and able to care for myself in the past 6 months.My cancer has not spread to distant parts of my body.I have had radiation therapy to my pelvic area before.I am mentally and physically able to follow the study's requirements.I have prostate cancer and am eligible for radiation therapy aimed at curing it.I am between 18 and 70 years old.My kidneys are working well, with a creatinine clearance over 30 mL/min.My blood and liver tests meet the required levels for treatment.I have been taking lisinopril or a similar drug in the last two months.
- Group 1: Control group
- Group 2: Intervention group
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this research continuing to accept participants?
"The clinicaltrials.gov information reveals that this particular medical trial is not currently seeking new participants, as the last update was on September 1st 2022 and it was initially posted January 15th 2023. Nevertheless, there are presently 1340 other trials actively recruiting patients."
Does this research encompass individuals who are over 40 years of age?
"This medical experiment is exclusively available to those between 18 and 70 years of age. In contrast, younger patients have access to 77 trials while elders can find 1334 opportunities for clinical trial participation."
To what demographic is this research open?
"This clinical trial is acquiescing seventy individuals diagnosed with prostate cancer, aged between 18 and 70. Crucially, they must meet the following criteria: a definitive diagnosis of adenocarcinoma of the prostate (and be candidates for curative-intent external beam radiation), proficiency in English reading, systolic blood pressure higher than 130mmHg at baseline, M0 stage according to standard imaging procedures within 180 days prior to enrollment, ECOG performance status from 0 to 2 before registration, creatinine clearance exceeding 30mL/min beforehand; hemoglobin level of 9.0 g/dL or more without transfusions nor growth"
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