This trial is evaluating whether Treatment will improve 4 primary outcomes and 6 secondary outcomes in patients with Malignancies. Measurement will happen over the course of 2 years.
This trial requires 60 total participants across 3 different treatment groups
This trial involves 3 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.
"Malignancies typically have a rapid growth in numbers, have the ability to spread to new tissue, and rarely have the ability to heal without any treatment." - Anonymous Online Contributor
"The American Cancer Society estimates that 56,780 new diagnoses of non-melanoma [skin cancer](https://www.withpower.com/clinical-trials/skin-cancer)s will be made in 2007. This is an estimated 4.6% of the U.S. population. Among the most common malignancies, lung and prostate cancers, and melanoma showed very high incidence rates in all age groups; however the American Cancer Society did not calculate an incidence estimate for colorectal cancer, breast cancer, stomach cancer, or pancreatic cancer." - Anonymous Online Contributor
"The cause of malignancies may be influenced by the physical environment in which they develop. Tobacco, diet, exposure to occupational exposures to carcinogens (e.g., asbestos, benzopyrene, lead, ultraviolet radiation and others), and infections with oncogenic viruses may be important environmental factors. Some of these factors are more important than others. The mechanism by which such factors cause the malignancy often may be dependent on the immune system. As malignancies are commonly associated with immunosuppression or the use of immunosuppressive medications such as corticosteroids, they are not always the causative agent of the malignancy." - Anonymous Online Contributor
"The concept of cure appears ambiguous when associated with malignant disease. It is unclear whether some subtypes of cancer can be cured or the cure is not feasible as long as a cure is not found for the disease. These observations encourage physicians and research researchers to focus their efforts on designing treatment plans that aim at providing symptomatic relief." - Anonymous Online Contributor
"The signs of malignancies include unusual appearance of the skin, change of vision, headache and abnormal behavior. The signs of malignancies may be not evident but are very important when they occur." - Anonymous Online Contributor
"Symptoms and complications typically arise from the underlying cancer and can result from treatment. Treatment of cancer may include surgery, chemotherapy, radiation therapy, and targeted therapy. Surgery, specifically debulking, is typically performed by specialists. Treatment of malignancies can be tailored to a patient depending on their stage of progression. Adjuvant treatment can be used to reduce progression of the cancer to metastases. Targeted treatment uses drugs or treatments specifically directed at the tumor in the hopes that it will decrease tumor growth and lead to fewer side effects and higher remission rates. Chemotherapy often provides temporary relief and is rarely used alone. Antipsychotics are effective in treating mood irregularities in schizophrenia." - Anonymous Online Contributor
"Although survival rates have improved for brain tumors in recent years, our knowledge of the biology of brain tumors remains limited. Many of the current therapies used to treat brain cancer may have been developed for other diseases or for other organs including the brain." - Anonymous Online Contributor
"Targeted therapies are proving effective and safe in a variety of cancer types. The high level of activity of the EGFR (EGFR inhibitor afatinib) and of Her2/neu (trastuzumab), as well as the high response rate to trastuzumab in Her2/neu-containing tumors, warrant exploration of the use of targeted therapy in patients with HER2/neu-expressing breast cancer." - Anonymous Online Contributor
"The common side effects of treatment include fatigue, nausea, vomiting, diarrhea, abdominal pain, dyspepsia, rash, itch, and joint pain. These common side effects should be evaluated by the patient before treatment. The clinician should be aware of these side effects and ask patients to report any side effects that are unexplained. All side effects should be evaluated by a medical professional for diagnosis." - Anonymous Online Contributor
"In this sample, most patients reported improvements in quality of life as a result of their illness and treatment. Future directions should involve assessing psychological and social variables when addressing quality of life for patients. Clinicians can incorporate patient perceptions and expectations into their clinical decision-making and treatment plans to aid in improving quality of life and treatment outcomes." - Anonymous Online Contributor
"Few patients received treatment in combination with any treatments other than radiotherapy. Treatment typically used in combination with radiotherapy was more commonly used than combination chemotherapy. The use of radiotherapy or radiation sensitization techniques had little influence on the use of chemotherapy and no influence on the use of radical radiotherapy only." - Anonymous Online Contributor
"Most people will have a malignancy at some point in their life. Physicians are often not sure what to expect when a malignancy develops. To facilitate patient education, we have developed guidelines for patients with non-Hodgkin lymphoma, [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer), cancer of the skin, and lung cancer. Physicians can use patients' medical records to review their illness and treatment, and patients can review their medical records themselves to obtain copies of their records. Our guidelines assist in informing patients from the very early stages of a malignancy until a cancer is definitively treated." - Anonymous Online Contributor