← Back to Search

Cardiac Biomarker Testing for Cardiac Toxicity

N/A
Waitlist Available
Led By Robert A. Wolff, MD
Research Sponsored by M.D. Anderson Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights

Study Summary

The goal of this clinical research study is to learn if certain biomarker testing on blood samples can help to detect heart damage that may occur during chemotherapy. Biomarkers are chemical "markers" found in the blood that may be related to heart function. High levels of these markers may be linked with heart problems such as heart damage.

Eligible Conditions
  • Cardiac Toxicity
  • Solid Tumors

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Use of Cardiac Biomarkers, B-type Natriuretic Peptide (BNP) and Troponin I (TnI), for Detecting Cardiotoxicity in Patients Undergoing Anthracycline-based Chemotherapy
Secondary outcome measures
Clinical management and outcomes of patients with abnormal cardiac biomarkers or clinically defined cardiotoxicity during chemotherapy
Sensitivity and specificity of serial LVEF measurements in detecting cardiotoxicity
Cardiotoxicity

Trial Design

1Treatment groups
Experimental Treatment
Group I: Cardiac Biomarker TestingExperimental Treatment2 Interventions
Biomarker testing for cardiac biomarkers, B-type natriuretic peptide (BNP) and Troponin I (TnI), and symptom questionnaires of participants undergoing anthracycline-based chemotherapy.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Questionnaires
2013
Completed Phase 2
~3330

Find a Location

Who is running the clinical trial?

Alere San DiegoIndustry Sponsor
9 Previous Clinical Trials
5,391 Total Patients Enrolled
M.D. Anderson Cancer CenterLead Sponsor
2,975 Previous Clinical Trials
1,788,912 Total Patients Enrolled
Robert A. Wolff, MDPrincipal InvestigatorM.D. Anderson Cancer Center
1 Previous Clinical Trials
31 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment (PREDICT)
2011. "Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment (PREDICT)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01032278.
All > Toxicity
~42 spots leftby May 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top