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PT plus translingual stimulation device for Multiple Sclerosis (NeuroMSTraLS Trial)

N/A
Waitlist Available
Led By Michelle Ploughman
Research Sponsored by University of Saskatchewan
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 27 weeks
Awards & highlights

NeuroMSTraLS Trial Summary

This trial will test if electrical stimulation in addition to physiotherapy can help improve walking and balance in people with MS.

Eligible Conditions
  • Multiple Sclerosis

NeuroMSTraLS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~27 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 27 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Dynamic Gait Index (DGI)
Timed 25 foot walk test (T25FWT)
Secondary outcome measures
Fatigue Scale for Motor and Cognitive Functions
Multiple Sclerosis Impact Scale (MSIS-29)
Multiple sclerosis walking scale - 12 item (MSWS-12)
+1 more

NeuroMSTraLS Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: PT+ DeviceExperimental Treatment1 Intervention
PT plus translingual stimulation device PoNS device will be used to deliver trans-lingual electrical stimulation. The stimulation will be delivered while the participants engages in evidence-based physiotherapy for walking and balance.
Group II: PT + Control DeviceActive Control1 Intervention
PT plus translingual stimulation control device Control device will be used. Participants will wear device while engaging in evidence-based physiotherapy for walking and balance.

Find a Location

Who is running the clinical trial?

University of SaskatchewanLead Sponsor
251 Previous Clinical Trials
154,358 Total Patients Enrolled
5 Trials studying Multiple Sclerosis
35,267 Patients Enrolled for Multiple Sclerosis
Memorial University of NewfoundlandOTHER
68 Previous Clinical Trials
1,831,970 Total Patients Enrolled
2 Trials studying Multiple Sclerosis
80 Patients Enrolled for Multiple Sclerosis
Michelle PloughmanPrincipal InvestigatorMemorial University of Newfoundland

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

How old are they?
18 - 65
What site did they apply to?
Memorial University of Newfoundland
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Neuromodulation in MS Using Translingual Stimulation
Sarah Donkers 2021. "Neuromodulation in MS Using Translingual Stimulation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05275049.
~14 spots leftby Apr 2025
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