ALS Clinical Trials 2022

Amyotrophic Lateral Sclerosis studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect als clinical trial in 2022.

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is an ALS clinical trial?

An ALS clinical trial is a study with human participants used to test new therapies for amyotrophic lateral sclerosis (ALS). These studies provide researchers with data to determine whether new treatments are effective, safe, and should be offered to those currently living with ALS. If you are looking to join an ALS clinical trial, Power can help you search recent trials by condition, treatment, or location.

What is the latest treatment for ALS?

The latest treatment for ALS is the FDA-approved Radicava. The drug was introduced in 2017, making it the first new ALS-specific treatment in 22 years. Radicava joins four other drugs which are approved by the FDA to treat ALS, along with Rilutek, Tiglutik, Exservan, and Nuedexta. You can find the most recent ALS clinical trials by using Power, which allows you to search trials tailored to your condition, location, and ideal treatment.

Has anyone been cured of ALS?

There is currently no cure or treatment that stops or reverses the progression of ALS. However, there are FDA-approved medications that can modestly slow the progression of the disease. There are currently several clinical trials being carried out worldwide that are revealing important information on how to treat ALS in the future. Power makes it easy to find ALS clinical trials tailored to your condition, treatment, or location.

Does ALS cause tiredness?

Fatigue is a common symptom of ALS, which is caused by muscle weakness and spasticity. However, the effects of fatigue can be minimized through effective treatment. By recognizing the signs of fatigue, understanding the factors that worsen symptoms, and learning to conserve energy, people with ALS can significantly improve their quality of life. To find active ALS clinical trials in your area, you can use Power to search by condition, treatment, or location.

How does Riluzole work against ALS?

Riluzole is a drug used to treat ALS, also known as Lou Gehrig's disease. Riluzole belongs to a class of medications called benzothiazoles. It works against ALS by altering the activity of natural substances in the body that affect the nerves and muscles. While Riluzole cannot cure ALS, it may slow its progression if taken as directed. If you are looking to join a prostate cancer clinical trial, Power can help you search recent trials by condition, treatment, or location.

What are the 3 types of ALS?

The 3 types of ALS are sporadic ALS, familial ALS, and Guamanian ALS. Sporadic ALS is the most common form in the U.S. and occurs without a known cause or familial association. Familial ALS is inherited by persons in the family who have the disease and represents a very small number of cases. Finally, Guamanian ALS refers to the high incidences of ALS in Guam and the Trust Territories of the Pacific. You can find the most recent ALS clinical trials by using Power, which allows you to search trials tailored to your condition, location, and ideal treatment.

Can ALS go into remission?

Not everyone with ALS experiences the same symptoms, and while symptoms may appear to remain the same over a period of time, it is a progressive disease which does not go into remission. ALS is a terminal condition with an average life expectancy of 2 to 5 years after diagnosis. However, some people with ALS have lived for 10 years or longer. Power makes it easy to find ALS clinical trials tailored to your condition, treatment, or location.

What age does ALS usually start?

While ALS can occur at any age, it is most common for symptoms to develop between the ages of 55 and 75. While men are slightly more likely to develop ALS than women, as people age the difference in frequency between the sexes disappears. To find active ALS clinical trials in your area, you can use Power to search by condition, treatment, or location.

What vitamins help ALS?

Dietary supplements commonly used by patients with ALS include vitamin E, B-vitamins such as folic acid, B6, and B12, zinc, melatonin, and creatine. Malnutrition and weight loss are common problems for those living with ALS, with inadequate dietary intake leading to muscular atrophy, a weakened immune system, and more frequent cases of infection. If you are looking to join an ALS clinical trial, Power can help you search recent trials by condition, treatment, or location.

How quickly does ALS progress?

It takes about 9 to 12 months on average for someone to be diagnosed with ALS after first noticing symptoms. If you are beginning to notice symptoms, it is important to get a professional evaluation as quickly as possible. Approved drugs like Rilutek can help delay the progression of ALS, and the sooner you start taking medication, the better. You can find the most recent ALS clinical trials by using Power, which allows you to search trials tailored to your condition, location, and ideal treatment.

Who gets ALS the most?

The majority of those who develop ALS are between the ages of 40 and 70, with an average age of 55 at the time of diagnosis. However, there are cases of ALS in people in their twenties and thirties. While ALS is 20 percent more common in men than women, cases are more equal between men and women with increasing age. Power makes it easy to find ALS clinical trials tailored to your condition, treatment, or location.

Does gabapentin help ALS?

While gabapentin is commonly used to treat partial seizures and neuropathic pain, it has been shown to prolong survival in those with familial ALS. It has also been shown to slow the decline of arm strength in those with sporadic ALS. To find active ALS clinical trials in your area, you can use Power to search by condition, treatment, or location.

Does ALS start with twitching?

Muscle twitches, also known as fasciculations, are one of the earliest symptoms of ALS, along with stiff muscles, muscle weakness, or difficulty chewing or swallowing. These symptoms can be so subtle that they are often overlooked when diagnosing the onset of ALS. If you are looking to join an ALS clinical trial, Power can help you search recent trials by condition, treatment, or location.

Can ALS be prevented?

While there is currently no definite method for preventing ALS, those living with the disease can join clinical trials that help researchers learn about the causes and risk factors of the disease. You can find the most recent ALS clinical trials by using Power, which allows you to search trials tailored to your condition, location, and ideal treatment.

Why do athletes get ALS?

A 2019 study found an association between developing ALS and professional sports prone to repetitive concussive head and neck trauma. Sports like American football and soccer, where both head and neck trauma are common, have an increased association with developing ALS. Power makes it easy to find ALS clinical trials tailored to your condition, treatment, or location.

Does ALS affect body temperature?

While ALS is not normally associated with defective thermoregulatory function, its progression can severely affect key brain regions for controlling body temperature. Further studies are necessary to determine if the body temperature regulatory system is a biomarker or modifier of disease progression for those with ALS. To find active ALS clinical trials in your area, you can use Power to search by condition, treatment, or location.

Who is most commonly diagnosed with ALS?

Most people who are diagnosed with ALS are between the ages of 40 and 70, although it can occur in younger individuals. ALS occurs around the world without racial, ethnic or socioeconomic boundaries. As many as 30,000 people in the United States live with ALS, with 5,000 new cases being diagnosed every year. If you are looking to join an ALS clinical trial, Power can help you search recent trials by condition, treatment, or location.

How fast is ALS progression?

While survival in ALS varies considerably, about one third of patients die within 12 months of being diagnosed. Early recognition of ALS is essential for patients to increase their lifespan through therapeutic interventions. You can find the most recent ALS clinical trials by using Power, which allows you to search trials tailored to your condition, location, and ideal treatment.

What state has the most cases of ALS?

Rates of ALS are highest in the Midwest, which includes states like Iowa, Illinois, Michigan, Minnesota, and Ohio. Rates of ALS in the Midwest were 5.5 cases per 100,000 in 2018, followed by the Northeast with 5.1 cases per 100,000. Power makes it easy to find ALS clinical trials tailored to your condition, treatment, or location.

What country has the most cases of ALS?

A 2016 study found that prevalence rates for ALS were highest in Uruguay, New Zealand, and the United States. Countries with the lowest cases of ALS were Serbia, China, and Taiwan. The age group with the highest prevalence of ALS were those from age 60 to 79. To find active ALS clinical trials in your area, you can use Power to search by condition, treatment, or location.