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Stem Cell Therapy

Stem Cell Therapy for Neurological Disorders (NEST Trial)

N/A

Recruiting

Led By Jeffrey Weiss, MD

Research Sponsored by MD Stem Cells

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Have documented functional damage to the central or peripheral nervous system unlikely to improve with present standard of care.

Be over the age of 18 and capable of providing informed consent.

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 0,1,3,6 and 12 months

Awards & highlights

NEST Trial Summary

This trial is testing whether injecting stem cells into the nose can help improve neurologic function in patients with certain conditions.

Who is the study for?

Adults over 18 with stable neurologic conditions like ALS, MS, stroke, or brain injuries not expected to improve with current treatments. They must be at least 6 months post-diagnosis and cleared by a doctor as safe for the procedure. Pregnant women or those who may become pregnant within 3 months post-treatment are excluded.Check my eligibility

What is being tested?

The trial is testing whether injecting patients' own bone marrow stem cells into their bloodstream and nasal passages can improve neurological function in various chronic diseases.See study design

What are the potential side effects?

Potential side effects aren't specified but could include typical risks associated with medical procedures such as infection, bleeding, or an adverse reaction to the stem cell transfer.

NEST Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have lasting nerve damage that current treatments can't fix.

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I am over 18 and can give my consent.

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I have lasting nerve damage that current treatments can't fix.

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I am over 18 and can give my consent.

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I have lasting nerve damage that current treatments can't improve.

Select...

I am over 18 and can give my consent.

NEST Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 0,1,3,6 and 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~0,1,3,6 and 12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 0,1,3,6 and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Neurologic Function

Secondary outcome measures

Neurologic Functioning

NEST Trial Design

1Treatment groups

Experimental Treatment

Group I: Arm 1- Intravenous and Intranasal BMSCExperimental Treatment1 Intervention

Intervention- Autologous bone marrow aspiration and separation of Bone Marrow Derived Stem Cell (BMSC) fraction then provided intravenously and intranasally (lower 1/3 of nasal passages).

0 / 6Eligibility criteria met

Find a Location

Who is running the clinical trial?

MD Stem CellsLead Sponsor

4 Previous Clinical Trials

940 Total Patients Enrolled

Jeffrey Weiss, MDPrincipal InvestigatorCoral Springs

4 Previous Clinical Trials

940 Total Patients Enrolled

Steven Levy, MDStudy ChairMD Stem Cells

4 Previous Clinical Trials

940 Total Patients Enrolled

Media Library

Intranasal BMSC (Stem Cell Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT02795052 — N/A

Neurological Disorders Research Study Groups: Arm 1- Intravenous and Intranasal BMSC

Neurological Disorders Clinical Trial 2023: Intranasal BMSC Highlights & Side Effects. Trial Name: NCT02795052 — N/A

Intranasal BMSC (Stem Cell Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02795052 — N/A

Neurological Disorders Patient Testimony for trial: Trial Name: NCT02795052 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the aggregate amount of people engaged in this medical study?

"Affirmative. According to the current information on clinicaltrials.gov, this research study is still enrolling participants. Launched June 1st 2016 and most recently updated November 25th 2022, it requires 500 volunteers from two medical locations."

Answered by AI

Does this clinical research require any new participants, and if so how would one sign up?

"As per the clinicaltrials.gov database, this medical trial is presently looking for participants and has been since June 1st 2016 with updates through November 25th 2022."

Answered by AI