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Non-invasive Brain Stimulation

Brain Stimulation for Dyslexia

N/A
Recruiting
Led By Katherine S. Aboud, PhD
Research Sponsored by Vanderbilt University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Right-handed native English monolingual speakers
Age range of subjects: minimum 18 years, maximum 40 years
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to 12 month
Awards & highlights

Study Summary

This trial will test a new brain stimulation protocol to see if it can help improve reading ability in adults with low literacy levels. If successful, this could change how we treat low adult literacy and have impacts on other clinical disorders.

Who is the study for?
This trial is for right-handed, native English-speaking adults aged 18-40 with dyslexia. Participants must not have a low IQ, developmental disorders, visual or hearing impairments that can't be corrected, metal devices in their body, recent migraines, severe fatigue or psychiatric issues. They should not be pregnant and mustn't take certain medications.Check my eligibility
What is being tested?
The study tests the effect of non-invasive brain stimulation on reading comprehension in adults with dyslexia. It compares different types of stimulations (RLN and CCN) against a sham intervention to see which improves reading skills and brain function.See study design
What are the potential side effects?
While the description doesn’t specify side effects, non-invasive brain stimulation may cause discomfort at the stimulation site, headache, lightheadedness or seizures in rare cases.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am right-handed and only speak English.
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I am between 18 and 40 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to 12 month
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 12 month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in reading comprehension ability on standardized test measure
Performance in reading comprehension ability on test measure during stimulation session
Secondary outcome measures
Change in brain activations during reading

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: Reading and Language Network (RLN)Experimental Treatment1 Intervention
Participants receiving real stimulation to the left angular gyrus and left temporal pole.
Group II: RLN and CCNExperimental Treatment1 Intervention
Participants receiving real stimulation to the left dorsolateral prefrontal cortex and left angular gyrus.
Group III: Cognitive Control Network (CCN)Experimental Treatment1 Intervention
Participants receiving real stimulation to the bilateral dorsolateral prefrontal cortices.
Group IV: Sham stimulationPlacebo Group1 Intervention
Participants receiving sham stimulation.

Find a Location

Who is running the clinical trial?

Vanderbilt UniversityLead Sponsor
704 Previous Clinical Trials
6,143,138 Total Patients Enrolled
4 Trials studying Dyslexia
1,144 Patients Enrolled for Dyslexia
National Institutes of Health (NIH)NIH
2,701 Previous Clinical Trials
7,506,651 Total Patients Enrolled
1 Trials studying Dyslexia
28 Patients Enrolled for Dyslexia
Katherine S. Aboud, PhDPrincipal InvestigatorVanderbilt University

Media Library

Dyslexia Clinical Trial 2023: CCN real non-invasive brain stimulation intervention Highlights & Side Effects. Trial Name: NCT05523505 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment open for participation in this trial?

"Unfortunately, the data present on clinicaltrials.gov claims that this trial is currently not searching for potential candidates. The experiment was first presented in December 15th 2022 and last updated August 28th 2022. However, there are 17 other medical studies actively enrolling participants at the moment."

Answered by AI

Are participants aged 25 and over qualified for this experiment?

"This medical trial is open to participants aged 18-40. There are 14 separate studies available for applicants younger than this age bracket, while a single study exists which caters to those over 65 years old."

Answered by AI

What types of individuals are appropriate for enrollment in this research?

"This research is looking to include 225 people with reading disability in the age bracket of 18-40. Eligibility criteria for participation are thus limited to those who satisfy these conditions."

Answered by AI

Who else is applying?

What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
0
What site did they apply to?
Vanderbilt University Medical Center

What questions have other patients asked about this trial?

it will be in written form?
PatientReceived 1 prior treatment
Recent research and studies
clinicaltrials.govStudy
Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults
Katherine Aboud 2022. "Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05523505.
All > Dyslexia
~109 spots leftby Aug 2025
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