19 Participants Needed

Computerized Memory Training for Mild Cognitive Impairment

(COMET Trial)

AC
SP
NN
Overseen ByNicole Nguyen, MA
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Vanderbilt University Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

The investigators propose to apply neuroplasticity-based computerized cognitive remediation (nCCR) to improve memory function in patients with Mild Cognitive Impairment (MCI).

Research Team

AC

Alexander C Conley, PhD

Principal Investigator

Vanderbilt University Medical Center

Eligibility Criteria

This trial is for adults aged 55-85 with Mild Cognitive Impairment (MCI), who have memory concerns but not severe dementia or Alzheimer's. Participants must be in good health, not pregnant, and fluent in English. They need a study partner available to assist during the study.

Inclusion Criteria

Have a subjective memory concern as reported by participant, study partner or clinician
Be between 55 and 85 years of age (inclusive)
Clinical Dementia Rating Global score of 0.5
See 9 more

Exclusion Criteria

Residence in a skilled nursing facility
Participants whom the Principal Investigator deems to be otherwise ineligible.
Use of any investigational drugs within 30 days or 5 half-lives, whichever is longer, prior to screening
See 6 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive 45 hours of Neuroplasticity-based Computerized Cognitive Remediation (nCCR) to improve memory function

6 weeks
Multiple visits (frequency not specified)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

  • Neuroplasticity-based Computerized Cognitive Remediation
Trial Overview The trial tests a computer program designed to improve memory by using exercises that stimulate brain plasticity. It aims to see if regular use of this cognitive training can enhance memory function in those with MCI.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Neuroplasticity-based Computerized Cognitive RemediationExperimental Treatment1 Intervention
Participants will receive a 45-hour of Neuroplasticity-based Computerized Cognitive Remediation

Find a Clinic Near You

Who Is Running the Clinical Trial?

Vanderbilt University Medical Center

Lead Sponsor

Trials
922
Recruited
939,000+
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of Service·Privacy Policy·Cookies·Security