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Procedure

Ureteroscopy for Kidney Stones (UPURS Trial)

N/A

Recruiting

Led By Thomas Chi, MD

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Presence of symptoms (pain, nausea, vomiting, hematuria)

Adult (> 18 yo)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 months

Awards & highlights

UPURS Trial Summary

This trial will compare two ways to treat a ureteral stone. One way is to start treatment right away, the other is to wait and see if it gets better.

Who is the study for?

The UPURS trial is for adults over 18 who come to the emergency department with symptoms like pain, nausea, vomiting, or blood in urine due to a ureteral stone that's at least 5mm big as seen on a CT scan. It's not for those with certain urinary structures, large stones unsuitable for URS, transplant kidneys, strong surgery preferences, need for stents due to other conditions, or untreated urinary infections.Check my eligibility

What is being tested?

This study compares two approaches: immediate ureteroscopy (a procedure using a scope to remove the stone) versus waiting and only performing the procedure if necessary later on. Participants are randomly assigned to one of these strategies when they show up at the hospital with kidney stone symptoms.See study design

What are the potential side effects?

Ureteroscopy can cause side effects such as discomfort or pain during and after the procedure, bleeding in urine temporarily post-operation, possible infection risk requiring antibiotics treatment and rarely injury to ureters which might need further surgical intervention.

UPURS Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am experiencing symptoms like pain, nausea, or blood in urine.

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I am over 18 years old.

UPURS Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Anxiety Score

Pain Score

Secondary outcome measures

Hospital visit length

Other outcome measures

Days of work lost

Hospital visits

UPURS Trial Design

2Treatment groups

Active Control

Group I: Group B (Observation/delayed ureteroscopy)Active Control1 Intervention

Group II: Group A (Upfront ureteroscopy)Active Control1 Intervention

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor

2,507 Previous Clinical Trials

15,238,475 Total Patients Enrolled

2 Trials studying Kidney Stones

3,471 Patients Enrolled for Kidney Stones

Thomas Chi, MDPrincipal InvestigatorUniversity of California, San Francisco

5 Previous Clinical Trials

400 Total Patients Enrolled

Media Library

Ureteroscopy (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT05715086 — N/A

Kidney Stones Research Study Groups: Group B (Observation/delayed ureteroscopy), Group A (Upfront ureteroscopy)

Kidney Stones Clinical Trial 2023: Ureteroscopy Highlights & Side Effects. Trial Name: NCT05715086 — N/A

Ureteroscopy (Procedure) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05715086 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies open for prospective participants in this experiment?

"As per the information hosted on clinicaltrials.gov, this experiment is not taking applications at present. The post was initially published on March 1st 2023 and last modified on February 2nd 2023; however, there are 54 other trials actively seeking participants right now."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones

2023. "UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05715086.