MAD-active for Oral Cancers

CHUM, Montréal, Canada
Oral Cancers+4 More ConditionsRonco-Onco and MAD - Device
Eligibility
18 - 65
All Sexes

Study Summary

This trial studied snoring and sleep apnea treatment with a MAD device in patients with OPC. Results show mixed success.

Eligible Conditions
  • Oral Cancers
  • Sleep Apnea
  • Throat Cancer
  • Oral Squamous Cell Carcinoma
  • Snoring

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
N/A

Study Objectives

2 Primary · 1 Secondary · Reporting Duration: Done in morning from 6-8 sleep period, assessed in morning of each of 3 nights

Done in morning from 6-8 sleep period, assessed in morning of each of 3 nights
Sleep quality
From sleep onset to wake time (6-8 hrs) in morning of night 1 for baseline vs difference of 2 or 3 according to ramdom allocation
Index apnea-hypopnea
Snoring

Trial Safety

Trial Design

2 Treatment Groups

MAD-active
1 of 2
Neutral MAD- control
1 of 2

Active Control

Non-Treatment Group

35 Total Participants · 2 Treatment Groups

Primary Treatment: MAD-active · Has Placebo Group · N/A

MAD-active
Device
ActiveComparator Group · 1 Intervention: Ronco-Onco and MAD · Intervention Types: Device
Neutral MAD- control
Device
ShamComparator Group · 1 Intervention: Ronco-Onco and MAD · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: done in morning from 6-8 sleep period, assessed in morning of each of 3 nights

Who is running the clinical trial?

Centre hospitalier de l'Université de Montréal (CHUM)Lead Sponsor
341 Previous Clinical Trials
116,929 Total Patients Enrolled

Eligibility Criteria

Age 18 - 65 · All Participants · 5 Total Inclusion Criteria

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Frequently Asked Questions

Is the age eligibility for this medical study restricted to those over 40 years old?

"This clinical experiment necessitates that participants are aged 18 to 65. There is a total of 44 separate trials for those younger than 18 and 777 dedicated studies for seniors above the age of 65." - Anonymous Online Contributor

Unverified Answer

Are there any openings for persons wishing to participate in this clinical trial?

"Absolutely. Clinicaltrials.gov confirms that the trial is currently recruiting, which commenced on February 3rd 2023 and was last updated on May 9th 2023. 35 participants will be recruited from a single site." - Anonymous Online Contributor

Unverified Answer

To what extent is this experiment involving human participants?

"Yes, the information on clinicaltrials.gov confirms that this research project is currently recruiting participants. This trial was initially advertised on February 3rd 2023 and recently updated on May 9th of the same year. Participants for this experiment will be accepted from one centre, with a total enrolment of 35 individuals." - Anonymous Online Contributor

Unverified Answer

Is there an opportunity to join this experiment?

"For this medical experiment, 35 people aged 18-65 with oral cancers are being recruited. The ideal candidate should have a diagnosis of oropharyngeal cancer and be either male or female; preference is given to males in a 1:4 ratio. Additionally, they must have undergone radiation therapy at the Radiation Oncology Department and report having snoring issues and/or breathing cessation while sleeping." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.