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tDCS + Speech-Language Therapy for Aphasia (AphasiatDCS Trial)

N/A

Recruiting

Research Sponsored by University of New Mexico

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Aged 25-85

Must have a diagnosis of aphasia based on impaired performance on the Western Aphasia Battery-Revised, Boston Naming Test, or during discourse production

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 months

Awards & highlights

AphasiatDCS Trial Summary

This trial will study whether a certain type of electrical brain stimulation can help people with aphasia improve their ability to communicate.

Who is the study for?

This trial is for individuals aged 25-85 who are more than a year post-stroke and have aphasia, which affects their language abilities. They must show left-hemisphere brain damage and be responsive to naming tasks. People with other neurological diseases, right hemisphere damage, mood disorders, recent substance abuse, electrical implants that interfere with tDCS or MRI scans, medical instability or pregnancy cannot participate.Check my eligibility

What is being tested?

The study tests if targeted Transcranial Direct Current Stimulation (tDCS) can improve speech-language therapy outcomes in people with chronic aphasia after a stroke. Participants will receive either active cathodal tDCS or placebo alongside language training for 15 days to see which is more effective.See study design

What are the potential side effects?

While the document doesn't specify side effects of tDCS in this context, common ones may include mild itching, tingling at the electrode site during stimulation, headache or fatigue afterwards. Serious side effects are rare.

AphasiatDCS Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 25 and 85 years old.

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I have been diagnosed with aphasia.

AphasiatDCS Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Naming Efficiency of trained items

Naming Response Time of trained items Scales - IV (WAIS-IV; Wechsler, Coalson, & Railford, 2008)

Picture Naming of trained items

Secondary outcome measures

Discourse informativeness - Main Concept Production

Efficiency of discourse informativeness - Main Concept Production

Naming Efficiency of untrained items - Boston Naming Test

+2 more

AphasiatDCS Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Experimental: Active cathodal tDCS + Speech-language trainingActive Control1 Intervention

In this arm, 31 patients with stroke induced Aphasia will undergo 15 sessions of active tDCS (x 30 minutes of stimulation) combined with 1 hour simultaneous speech-language training on consecutive weekdays.

Group II: Comparator: Placebo cathodal tDCS + Speech-language trainingPlacebo Group1 Intervention

In this arm, 31 patients with stroke induced Aphasia will undergo 15 sessions of sham tDCS (x 30 minutes sham) combined with 1 hour simultaneous speech-language training on consecutive weekdays..

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

National Institute on Deafness and Other Communication Disorders (NIDCD)NIH

330 Previous Clinical Trials

178,421 Total Patients Enrolled

37 Trials studying Aphasia

2,739 Patients Enrolled for Aphasia

National Institutes of Health (NIH)NIH

2,701 Previous Clinical Trials

7,506,826 Total Patients Enrolled

8 Trials studying Aphasia

1,752 Patients Enrolled for Aphasia

National Institute of General Medical Sciences (NIGMS)NIH

269 Previous Clinical Trials

247,062 Total Patients Enrolled

Media Library

Experimental: Active cathodal tDCS + Speech-language training Clinical Trial Eligibility Overview. Trial Name: NCT04432883 — N/A

Aphasia Research Study Groups: Experimental: Active cathodal tDCS + Speech-language training, Comparator: Placebo cathodal tDCS + Speech-language training

Aphasia Clinical Trial 2023: Experimental: Active cathodal tDCS + Speech-language training Highlights & Side Effects. Trial Name: NCT04432883 — N/A

Experimental: Active cathodal tDCS + Speech-language training 2023 Treatment Timeline for Medical Study. Trial Name: NCT04432883 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research endeavor currently need participants?

"Affirmative. Data hosted on clinicaltrials.gov affirms that this medical trial, first posted on December 1st 2016 and updated as recently as December 12th 2022, is actively searching for participants. Fifty patients need to be recruited from one respective medical centre."

Answered by AI

How many participants have been enlisted in the clinical experiment?

"Affirmative, the clinical trials platform states that this study is actively looking for patients. The trial was first posted on December 1st 2016 and has been updated as recently as December 12th 2022; 50 participants are needed from a single location."

Answered by AI

Does this investigation accept participants aged 80 or less?

"This study is searching for patient between the ages of 25 and 85. However, there are numerous medical studies available to those who fall outside this age range; 43 trials have been established for minors aged 18 or younger, with 1065 clinical investigations earmarked for persons above 65 years old."

Answered by AI

What is the overarching aim of this experiment?

"This clinical trial aims to evaluate the Naming Response Time of trained items Scales - IV (WAIS-IV; Wechsler, Coalson, & Railford, 2008) over a period of 3 months. Secondary objectives include Picture Naming of untrained items - Boston Naming Test which assesses change in naming accuracy for 60 pictured items with higher scores indicating improvement, as well as assessing changes in response time and efficiency when naming untrained words on the same test."

Answered by AI

To whom is enrollment in this clinical research available?

"To be eligible for this trial, individuals must possess aphasia and fit within the age range of 25-85. This clinical research is looking to recruit approximately fifty participants."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

Jessica Richardson 2022. "Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04432883.

All > Aphasia > Stroke