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Retinal Blood Flow Assessment for Glaucoma
Study Summary
This trial will help establish if changes in retinal blood flow could be an early marker for primary open angle glaucoma.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have been diagnosed with secondary glaucoma.I have had eye surgery, but only for cataracts or glaucoma.I have eye conditions that affect pressure measurements.I have a condition that affects the thickness of my retina's nerve layer.I have early-stage glaucoma without clear vision loss.I have diabetes, high blood pressure, or a blood vessel disease.I have early-stage glaucoma with specific vision field issues.I am over 18 years old.I have a cataract that is moderately severe or worse.My age matches that of the early glaucoma study participants.You have a gonioscopy grade 3 or 4.I am the same age as the early glaucoma study participants.I am over 18 years old.
- Group 1: Isocapnic Oxygen
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is eligibility for this research study limited to adults over the age of 18?
"Eligible candidates for this medical trial must be 18 to 88 years of age. For those under the legal threshold, there are 23 trials available and 192 for seniors over 65."
What is the upper bound of participants engaged in this research project?
"Affirmative. According to the clinicaltrials.gov page, this clinical trial is actively recruiting people and was initially posted on May 23rd 2022 with recent edits made on July 19th 2022. The study seeks 90 participants from four different medical centres."
Who would be eligible to volunteer for this research trial?
"This medical study seeks to recruit 90 people with glaucoma, aged between 18 and 88. In order to be eligible, applicants must meet specific criteria: they have to be over 18 years old; present early stages of the condition according to Hodapp-Anderson-Parrish Criteria; display no definite visual field defects upon standardised automated perimetry assessments (three consecutive exams); lack family history of the disease; feature OCT readings within normal range for their age group in all four quadrants; possess reliable visual fields as deemed by a glaucoma specialist with normal hemifields test values - three or more abnormal"
What risks could a patient face when undergoing Ocular Imaging with Optical Coherence Tomography (OCT) and Adaptive Optics (AO)?
"There is clinical evidence in favour of Ocular Imaging with Optical Coherence Tomography (OCT) and Adaptive Optics' safety, so it was awarded a score of 3."
Is this research project currently enlisting participants?
"Affirmative, the patient recruitment process is still ongoing. The trial was initially published on May 23rd 2022 and has since been updated twice; most recently on July 19th of this year. 90 volunteers are needed to be recruited from 4 different medical facilities."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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