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Corticosteroid

Corticosteroids for Optic Neuritis

N/A

Waitlist Available

Research Sponsored by National Eye Institute (NEI)

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Acute unilateral optic neuritis with visual symptoms for 8 days or less

Age range of 18 to 46 years

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 years

Awards & highlights

Study Summary

This trial will help researchers understand the effects of corticosteroid treatment for optic neuritis, the natural history of the disease, and identify risk factors for developing multiple sclerosis.

Who is the study for?

This trial is for individuals aged 18 to 46 who are experiencing their first episode of acute unilateral optic neuritis with visual symptoms starting within the last 8 days. Participants should not have any systemic disease causing the optic neuritis other than multiple sclerosis, and no prior corticosteroid treatment for optic neuritis or MS.Check my eligibility

What is being tested?

The study aims to evaluate the effects of corticosteroids on optic neuritis, understand how vision recovers naturally from this condition, and identify factors that may predict the development of multiple sclerosis in patients suffering from optic neuritis.See study design

What are the potential side effects?

While specific side effects are not listed here, corticosteroid treatments can generally include increased risk of infections, changes in mood or behavior, elevated blood sugar levels, bone weakening (osteoporosis), weight gain and fluid retention.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have had sudden vision problems in one eye for no more than 8 days.

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I am between 18 and 46 years old.

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I have never had optic neuritis in the affected eye.

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I have a vision and pupil reaction issue in one eye.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

National Eye Institute (NEI)Lead Sponsor

546 Previous Clinical Trials

1,401,928 Total Patients Enrolled

3 Trials studying Optic Neuritis

8 Patients Enrolled for Optic Neuritis

Media Library

Corticosteroid (Corticosteroid) Clinical Trial Eligibility Overview. Trial Name: NCT00000147 — N/A

Optic Neuritis Clinical Trial 2023: Corticosteroid Highlights & Side Effects. Trial Name: NCT00000147 — N/A

Corticosteroid (Corticosteroid) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00000147 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

At how many locations can participants access this clinical trial?

"This clinical trial is presently enrolling patients at 15 sites, including Little Rock, Ann Arbor and Philadelphia. For the convenience of those involved in this study, it is advised to find a medical centre nearby one's location to reduce travel necessities."

Answered by AI

Does this research protocol extend to geriatric participants?

"As per the rules of entry, only those aged 18-46 may partake in this clinical trial."

Answered by AI

Are there any remaining vacancies available to prospective participants in this investigation?

"The information hosted on clinicaltrials.gov shows that this trial is not presently seeking participants, having been first posted in July 1988 and last edited in May 2006. However, 407 other medical studies are actively recruiting patients."

Answered by AI