This trial involves 0 different treatment group
"Although only 5% of patients will develop optic neuritis, it can be severe and irreversible. It results in temporary loss of visual function. Its cause is unknown but it is more common in females than in men and in European than in Asian populations. It has a high fatality rate. Optic neuritis represents a disease process that can occur at any age but most commonly takes place in children and young adults. It may cause permanent neurological dysfunction. Nucleoside triphosphates (i.e. cellular energy) are important to nerve function and are found in all cellular nuclei. In optic neuritis the function of nerve cells in the brain is damaged. Neurofilament subunits are the structural basis for nerve fibre fibers." - Anonymous Online Contributor
"Each year, approximately 3% of American adults (about 3.5 million) are diagnosed with some form of optic neuritis. In one year, about 25% of all American adults will experience some form of new-onset visual loss." - Anonymous Online Contributor
"Although the exact cause of optic neuritis is not yet completely understood, the most common causes are infections, autoimmune diseases and nutritional deficiencies. The disease can be associated with vitamin B, and chronic alcoholism may exacerbate it." - Anonymous Online Contributor
"Some of the symptoms of optic neuritis may include sudden onset to painful progressive loss of vision (nystagmus, photophobia, floaters, light sensitivity, visual acuity, color loss, amaurosis fugax and photopsia), bilateral visual loss (amaurotis/amaurosis fugax) and unilateral visual loss (hemianopsia, photopsia, tunnel vision, monocular tunnel vision). \n\nOptic neuritis is an inflammatory condition of the optic nerve that manifests as vision loss (often temporary) in one or both eyes. It can affect both eyes or only one eye. Often, both eyes are not affected and the person has no sensory symptoms. Symptoms can be gradual." - Anonymous Online Contributor
"Findings from a recent study is a retrospective review in which subjects were treated based solely on clinical findings and patient-reported outcomes. Additional studies, including randomized controlled trials of therapeutic modalities used to treat optic neuritis, are needed to confirm our findings." - Anonymous Online Contributor
"It appears that corticosteroids are probably the first-line treatment for most instances of acute optic neuritis, though some recent studies suggest that their use appears less necessary in the more acute types. Other drugs frequently used (e.g. immunosuppressants, acetylcholinesterase inhibitors, etc.) tend to be either inappropriate or ineffective for optic neuritis, although their possible use should be further verified in some cases. Generally, an ophthalmologist or optometrist is the doctor who should be consulted due to the importance of early diagnosis and treatment." - Anonymous Online Contributor
"A small but statistically significant increase in QoL was observed in those receiving medication, but this did not translate into a clinically meaningful improvement in the patients' global QRS. Findings from a recent study was not powered to detect a clinically meaningful difference based on the clinical presentation in this group." - Anonymous Online Contributor
"[Optic neuritis must be treated aggressively with a combination of corticosteroids and antiviral medication and/or a combination of corticosteroids, penicilins, and antiviral medication, all injected inside the eye's optic disc, if at all possible.] There is still not enough research on the best way to inject the medications inside the eye. The best way to understand how to administer the medications is through clinical trials, where doctors, or researchers study medicines on patients to find the best way to make the drugs more or less safe and effective. [Power] can help guide patients toward the best trial for them." - Anonymous Online Contributor
"We have identified an additional family with optic neuritis that carries a mutation in optineurin, and this may be a useful addition to the genotypic markers already listed as predisposing genetic factors." - Anonymous Online Contributor
"The main cause of ON was a bacterial infection and the primary pathogens were Enterococcus faecalis and Streptococcus pyogenes. The main cause of retrobulbar neuritis was an aseptic meningitis." - Anonymous Online Contributor
"[Treatments for optic neuropathy(s) or optic neuritis have become advanced. For the former a steroid is now the therapy of choice for optic neuropathy in most countries where this has become available. Steroid sparing regimes have also become common for optic neuropathy. Optic neuritis is often a self-resolving condition now but can respond to treatments in time. A recent review of therapeutic regimens is available.]<br>\nTherapeutic approaches with potential or proven efficacy in the treatment of optic neuritis may include:\n\n- Anti-bacterial treatment as the primary treatment is used." - Anonymous Online Contributor
"We found that a significant proportion of patients with ON had a history of [allergy](https://www.withpower.com/clinical-trials/allergy). It is not always practical to exclude people such as this from treatment. We did not assess the severity of ON and do not consider it crucial to exclude patients with mild or early ON. Findings from a recent study support further studies to assess the prevalence of other, as yet unrecognised allergies in patients with ON." - Anonymous Online Contributor