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Tai Ji Quan for Mild Cognitive Impairment

N/A

Waitlist Available

Led By Fuzhong Li, Ph.D.

Research Sponsored by Oregon Research Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 6 months

Awards & highlights

Study Summary

This trial will test whether a cognitively enhanced exercise intervention can improve global cognitive function and dual-task ability in older adults with mild cognitive impairment.

Who is the study for?

This trial is for older adults with mild cognitive impairment who can safely exercise and have a CDR score ≤0.5 and MMSE ≥24, indicating normal general cognitive function. They must be willing to follow the study's protocol for 24 weeks plus a 6-month follow-up but not already engaged in Tai Ji Quan or similar vigorous physical activities.Check my eligibility

What is being tested?

The trial tests 'Tai Ji Quan: Moving to Maintain Brain Health,' an exercise program designed to improve overall brain function and the ability to do two things at once (dual-task ability) in older adults with mild cognitive issues.See study design

What are the potential side effects?

Since this intervention involves physical activity, potential side effects may include typical exercise-related risks such as muscle soreness, fatigue, or falls. However, participants are screened beforehand to ensure they can exercise safely.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Montreal Cognitive Assessment

gait under a dual-task condition - walking with no cognitive task, walking with a concurrent cognitive task

Secondary outcome measures

Clinical Dementia Rating

Computerized cognitive battery tests

Paper-and-pencil domain-specific cognitive battery tests

+1 more

Other outcome measures

Activity and movement confidence scales

Depression - Geriatric Depression Scale (GDS)

Physical activity - International Physical Activity Questionnaire (IPAQ)

+2 more

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: Cognitively enhanced Tai Ji QuanExperimental Treatment1 Intervention

Participants in this arm will exercise a series of Tai Ji Quan-based movements with configurations that are specifically designed for older adults to improve cognitive function, dual-task ability, strength/balance, and mobility.

Group II: Standard Tai Ji QuanActive Control1 Intervention

Serving as an active comparison arm, participants in this intervention will exercise a series of Tai Ji Quan-based movements that are specifically designed for older adults to improve strength/balance, cognitive function, and mobility.

Group III: StretchingPlacebo Group1 Intervention

Serving as a control arm, participants in this intervention will engage in a series of light exercise activities consisting of breathing, stretching, and body relaxation.

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Oregon Research InstituteLead Sponsor

84 Previous Clinical Trials

65,935 Total Patients Enrolled

Fuzhong Li, Ph.D.Principal InvestigatorOregon Research Institute

4 Previous Clinical Trials

1,445 Total Patients Enrolled

Media Library

The Go for Exercise & Healthy Aging Project Clinical Trial Eligibility Overview. Trial Name: NCT04070703 — N/A

Mild Cognitive Impairment Research Study Groups: Cognitively enhanced Tai Ji Quan, Standard Tai Ji Quan, Stretching

Mild Cognitive Impairment Clinical Trial 2023: The Go for Exercise & Healthy Aging Project Highlights & Side Effects. Trial Name: NCT04070703 — N/A

The Go for Exercise & Healthy Aging Project 2023 Treatment Timeline for Medical Study. Trial Name: NCT04070703 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the overarching goals of this investigation?

"This trial has been designed to assess Montreal Cognitive Assessment across a 6-month period. Other objectives include appraising the Physical performance - Functional Reach; Short Physical Performance Battery (change in physical performance from baseline to 24 weeks), Clinical Dementia Rating (shift in cognitive decline from baseline to 24 weeks) and Computerized cognitive battery tests (deviation in domain-specific cognitive function from baseline to 24 weeks)."

Answered by AI

May I participate in this experiment?

"This investigation is recruiting 332 senior citizens (65-95 years old) with mild cognitive impairment. To be selected, they must exhibit a willingness to participate in the 24 week trial and 6 month follow up process, express memory deficits, have a Clinical Dementia Rating score of 0.5 or lower, and provide evidence that their physical health allows for safe exercise as judged by a healthcare provider."

Answered by AI

Are participants being taken in for this research endeavor?

"This trial is currently not recruiting candidates, as indicated on clinicaltrials.gov; it was first posted in October of 2019 and modified most recently in July of 2022. However, there are 569 other studies that presently welcome participants to join their trials."

Answered by AI