332 Participants Needed

Tai Ji Quan for Mild Cognitive Impairment

FL
Overseen ByFuzhong Li, Ph.D.
Age: 65+
Sex: Any
Trial Phase: Academic
Sponsor: Oregon Research Institute
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

To determine the efficacy of a cognitively enhanced exercise intervention - Tai Ji Quan: Moving to Maintain Brain Health in improving global cognitive function and dual-task ability in older adults with mild cognitive impairment.

Who Is on the Research Team?

FL

Fuzhong Li, Ph.D.

Principal Investigator

Oregon Research Institute

Are You a Good Fit for This Trial?

This trial is for older adults with mild cognitive impairment who can safely exercise and have a CDR score ≤0.5 and MMSE ≥24, indicating normal general cognitive function. They must be willing to follow the study's protocol for 24 weeks plus a 6-month follow-up but not already engaged in Tai Ji Quan or similar vigorous physical activities.

Inclusion Criteria

Clinical dementia rating (CDR) scale score ≤0.5
Having normal general cognitive function screened, with MMSE ≥24
My doctor says I can safely exercise.
See 2 more

Exclusion Criteria

I do not have any health conditions like severe heart failure or cancer spread that would limit my physical activity or survival.
You have been doing intense physical activities like Tai Ji Quan, brisk walking for 30 minutes or more at a time, or weight lifting on 3 or more days per week for the past 3 months.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in Tai Ji Quan-based exercises designed to improve cognitive function, dual-task ability, strength/balance, and mobility

24 weeks
Regular sessions (in-person)

Follow-up

Participants are monitored for changes in cognitive function, physical performance, and quality of life

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • The Go for Exercise & Healthy Aging Project
Trial Overview The trial tests 'Tai Ji Quan: Moving to Maintain Brain Health,' an exercise program designed to improve overall brain function and the ability to do two things at once (dual-task ability) in older adults with mild cognitive issues.
How Is the Trial Designed?
3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: Cognitively enhanced Tai Ji QuanExperimental Treatment1 Intervention
Group II: Standard Tai Ji QuanActive Control1 Intervention
Group III: StretchingPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Oregon Research Institute

Lead Sponsor

Trials
87
Recruited
62,600+
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