Lower Body Elevation for Low Blood Pressure

Overseen By Erikka Washington

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: The University of Texas Health Science Center, Houston

Disqualifiers: Pregnancy, Prisoners, Emergency surgery, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

200 Participants Needed

Trial Summary

What is the purpose of this trial?

The purpose of this study is to determine if lower extremity elevation (LEE) will reduce the incidence of postinduction hypotension, to compare the utilization of vasoactive medications after induction in patients with LEE and patients without LEE and to determine if LEE will increase measured cardiac output

Research Team

Ranganathan Govindaraj, MD

Principal Investigator

The University of Texas Health Science Center, Houston

Eligibility Criteria

This trial is for patients with a moderate or lower risk during anesthesia (ASA 3 or below) who need general anesthesia but aren't pregnant, allergic to common anesthetic drugs, requiring emergency surgery, rapid induction, or are prisoners.

Inclusion Criteria

My health is stable enough for surgery.

I need general anesthesia for my treatment.

Exclusion Criteria

I am allergic to common anesthesia drugs like fentanyl and propofol.

Pregnant women

I need a fast-acting anesthesia for my procedure.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Induction and Treatment

Participants undergo induction of general anesthesia with or without lower extremity elevation (LEE) to assess hemodynamic stability

1 day

1 visit (in-person)

Immediate Follow-up

Participants are monitored for hypotension and nadir blood pressure immediately after induction

5 minutes

Follow-up

Participants are monitored for any delayed effects post-anesthesia

1 week

Treatment Details

Interventions

• Lower Extremity Elevation

Trial Overview The study tests if raising the legs (LEE) can prevent low blood pressure after starting general anesthesia. It compares how often vasoactive drugs are used and checks if LEE affects cardiac output in patients with and without leg elevation.

Participant Groups

Group I: Group 1: LEE Experimental Treatment 1 Intervention

Group II: Group 2: no LEE Active Control 1 Intervention

Who Is Running the Clinical Trial?

The University of Texas Health Science Center, Houston

Lead Sponsor

Trials

974

Recruited

361,000+