Lower Body Elevation for Low Blood Pressure
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether lifting the legs (lower extremity elevation) can prevent low blood pressure after general anesthesia. Researchers aim to determine if this simple action reduces the need for certain blood pressure medications and improves heart function. The trial includes two groups: one with leg elevation and one without. It suits individuals who require general anesthesia and have no allergies to common anesthesia medications. As an unphased trial, it provides a unique opportunity to contribute to understanding simple, non-invasive methods for improving recovery after surgery.
Do I need to stop my current medications for the trial?
The trial information does not specify if you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that lower extremity elevation is safe for reducing postinduction hypotension?
Research shows that raising the legs safely manages low blood pressure. Studies have found that this method can significantly reduce the risk of low blood pressure after surgeries involving spinal anesthesia, sometimes cutting the risk by nearly half.
Raising the legs is non-invasive, requiring no surgery or medication, which often results in fewer side effects. Many patients find it easy to tolerate, and no serious side effects have been reported with this method.
Overall, current evidence suggests that raising the legs is a safe option for managing low blood pressure without medications.12345Why are researchers excited about this trial?
Researchers are excited about the Lower Extremity Elevation (LEE) technique for managing low blood pressure because it offers a simple, non-invasive approach that differs from standard treatments like medication or compression garments. Unlike these more traditional methods, which can involve side effects or require ongoing management, LEE is a mechanical technique that involves raising the legs to increase blood flow to the heart, potentially stabilizing blood pressure quickly. This straightforward method could provide an immediate and accessible option for those experiencing sudden low blood pressure, making it a promising area of exploration.
What evidence suggests that lower extremity elevation is effective for reducing postinduction hypotension?
Research has shown that raising the legs, known as lower extremity elevation (LEE), might help prevent low blood pressure after certain medical procedures. Some studies suggest that LEE can reduce the risk of low blood pressure after spinal procedures by up to 47%. This method improves blood flow back to the heart, helping to stabilize blood pressure. However, not all research agrees, and some studies find it less effective during surgery. In this trial, participants will be divided into two groups: one group will receive LEE, while the other will not. Overall, LEE is a simple and promising approach, but its effectiveness can vary depending on the situation.13467
Who Is on the Research Team?
Ranganathan Govindaraj, MD
Principal Investigator
The University of Texas Health Science Center, Houston
Are You a Good Fit for This Trial?
This trial is for patients with a moderate or lower risk during anesthesia (ASA 3 or below) who need general anesthesia but aren't pregnant, allergic to common anesthetic drugs, requiring emergency surgery, rapid induction, or are prisoners.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Induction and Treatment
Participants undergo induction of general anesthesia with or without lower extremity elevation (LEE) to assess hemodynamic stability
Immediate Follow-up
Participants are monitored for hypotension and nadir blood pressure immediately after induction
Follow-up
Participants are monitored for any delayed effects post-anesthesia
What Are the Treatments Tested in This Trial?
Interventions
- Lower Extremity Elevation
Trial Overview
The study tests if raising the legs (LEE) can prevent low blood pressure after starting general anesthesia. It compares how often vasoactive drugs are used and checks if LEE affects cardiac output in patients with and without leg elevation.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Find a Clinic Near You
Who Is Running the Clinical Trial?
The University of Texas Health Science Center, Houston
Lead Sponsor
Citations
Effectiveness of Leg Elevation to Prevent Spinal ...
Additionally, leg elevation reduces risk of developing postspinal hypotension by 47%. The result of our study is in line with the study ...
2.
bmcanesthesiol.biomedcentral.com
bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-025-03299-1Limited effect of leg elevation in preventing intraoperative ...
In conclusion, leg elevation did not significantly reduce the incidence of intraoperative hypotension or cerebral desaturation; however, it ...
3.
dovepress.com
dovepress.com/effectiveness-of-leg-elevation-to-prevent-post-spinal-hypotension-in-e-peer-reviewed-fulltext-article-OASLeg-elevation to Prevent Post-Spinal Hypotension | OAS
A majority of the evidence revealed that leg elevation following spinal anaesthesia in a caesarean delivery was effective in preventing post-spinal-induced ...
Spinal Hypotension In Lower Abdominal Surgeries
Leg elevation, a simple mechanical technique, has been explored as an effective means to improve venous return and mitigate hypotension. By ...
Effect of lower leg compression during cesarean section on ...
A positive correlation is identified between the muscle mass volume compressed and the elevation in blood pressure. In-depth analysis of this ...
Lower Body Elevation for Low Blood Pressure
... Lower Extremity Elevation will have tolerable side effects & efficacy for patients with Low Blood Pressure and Low blood pressure. See if you qualify today!
The influence of thirty-degree leg elevation on noradrenaline ...
A radioisotope scan study demonstrated that a 20-degree leg elevation resulted in a 34% redistribution of blood volume toward the central ...
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