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200mg GCE +200mg DHB for Healthy Subjects

N/A

Recruiting

Led By Chris McGlory

Research Sponsored by Queen's University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up -30 minutes, 0 minutes, 60 minutes, 120 minutes, during the oral glucose tolerance test.

Awards & highlights

Study Summary

This trial aims to investigate the effects of taking green coffee extract (GCE) on blood sugar levels in healthy adults. GCE has been shown to have positive effects on glucose metabolism and weight management.

Who is the study for?

This trial is for healthy men and women aged 18-40, with a BMI of 18.5-30, who don't smoke or have cardiovascular/metabolic diseases. Participants should have stable weight and not be on most oral contraceptives.Check my eligibility

What is being tested?

The study tests the effects of green coffee extract (GCE) combined with different doses of DHB and ALA versus placebo on blood sugar levels in adults after they consume a carbohydrate drink.See study design

What are the potential side effects?

Potential side effects are not detailed in the provided information but could include typical reactions to supplements such as digestive discomfort or allergic reactions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ -30 minutes, 0 minutes, 60 minutes, 120 minutes, during the oral glucose tolerance test.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~-30 minutes, 0 minutes, 60 minutes, 120 minutes, during the oral glucose tolerance test.

This trial's timeline: 3 weeks for screening, Varies for treatment, and -30 minutes, 0 minutes, 60 minutes, 120 minutes, during the oral glucose tolerance test. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

2-hour plasma glucose incremental area under the curve

Secondary outcome measures

2- hour plasma insulin incremental area under the curve

Appetite perceptions

Insulin sensitivity

+5 more

Trial Design

4Treatment groups

Experimental Treatment

Placebo Group

Group I: 200mg GCE +400mg ALAExperimental Treatment1 Intervention

200mg green coffee extract +200mg alpha-lipoic acid

Group II: 200mg GCE +200mg DHBExperimental Treatment1 Intervention

200mg green coffee extract + 200mg dihydroberberine

Group III: 200mg GCE +200mg ALAExperimental Treatment1 Intervention

200mg green coffee extract +200mg alpha-lipoic acid

Group IV: PlaceboPlacebo Group1 Intervention

Placebo supplement consisting of microcrystalline cellulose with 5mg magnesium stearate and 5mg silicon dioxide.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Queen's UniversityLead Sponsor

365 Previous Clinical Trials

120,397 Total Patients Enrolled

Dr. Chris McGlory, PhDLead Sponsor

2 Previous Clinical Trials

58 Total Patients Enrolled

Iovate Health Sciences International IncIndustry Sponsor

5 Previous Clinical Trials

179 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any available slots for patients to participate in this research study?

"Indeed, the data available on clinicaltrials.gov confirms that this study is actively seeking eligible patients. The initial posting of the trial took place on December 1st, 2023, and it was last modified on December 13th, 2023. The enrollment target for this investigation is to recruit a total of 20 participants from a single designated site."

Answered by AI

Is there an age limitation for participation in this medical study, specifically excluding individuals below a certain threshold of maturity?

"To be considered for participation in this study, applicants must have an age within the range of 18 to 45. It is worth noting that there are a total of 61 clinical trials specifically designed for individuals under the age of 18 and another 398 trials targeting patients over the age of 65."

Answered by AI

Do I meet the necessary criteria to participate in this experimentation?

"This research study aims to enroll 20 healthy volunteers aged between 18 and 45 years. To be eligible, individuals must meet the following requirements: males and females aged 18-40 with a body mass index (BMI) ranging from 18.5 to 30 kg/m2, no prior history of smoking or cardiovascular/metabolic conditions such as stroke, hypertension, or type II diabetes that could potentially affect the outcomes of the study. Additionally, participants should have maintained a stable weight within ±2kg for at least six months and demonstrate overall good health based on medical evaluations and physical activity questionnaires. The use of oral contracept"

Answered by AI

What is the current number of patients undergoing treatment in this medical study?

"Indeed, the data available on clinicaltrials.gov confirms that this ongoing study is actively seeking eligible participants. The trial was initially posted on December 1st, 2023 and last edited on December 13th, 2023. There is a need to recruit a total of 20 participants from a single designated site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

The Effect of Green Coffee Extract on Blood Glucose Homeostasis in Healthy Adults

Dr. Chris McGlory, PhD 2023. "The Effect of Green Coffee Extract on Blood Glucose Homeostasis in Healthy Adults". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06137066.