Antioxidant Cocktail for Stroke Prevention
Trial Summary
What is the purpose of this trial?
This trial tests a special mix of vitamins to see how it affects brain blood flow in healthy young adults. Researchers want to know if men and women respond differently to high oxygen levels.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking all current medications, but it does require stopping hormonal birth control at least one month before the first study visit if it's used for contraception only. Cardiovascular medication use is also an exclusion criterion, so you may need to stop those if applicable.
What data supports the effectiveness of the Antioxidant Cocktail treatment for stroke prevention?
Is the Antioxidant Cocktail safe for humans?
How does the antioxidant cocktail treatment for stroke prevention differ from other treatments?
The antioxidant cocktail for stroke prevention is unique because it combines multiple antioxidants, potentially enhancing neuroprotection by reducing brain damage from free radicals during a stroke. Unlike conventional treatments, this approach uses a combination of ingredients like resveratrol and lipoic acid, which have shown promise in animal models for reducing stroke damage.23489
Research Team
William G Schrage, PhD
Principal Investigator
University of Wisconsin, Madison
Eligibility Criteria
Healthy adults aged 18-40 can join this study on reactive oxygen species and brain blood flow. Excluded are those with high blood pressure, glucose levels, or a history of heart, liver, kidney diseases; smokers; certain medication users; MRI contraindications; women with irregular menstrual cycles or using hormonal birth control (except copper IUDs).Inclusion Criteria
Exclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo CBF testing in MRI under normoxia and hyperoxia conditions with either placebo or antioxidant cocktail
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Antioxidant Cocktail (Other)
- Placebo (Other)
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Wisconsin, Madison
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator