contrast-enhanced ultrasound for Traumatic Abdomen

Phase-Based Progress Estimates
3
Effectiveness
3
Safety
Traumatic Abdomencontrast-enhanced ultrasound - Device
Eligibility
No minimum age - 17
All Sexes
What conditions do you have?
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Study Summary

This trial studied whether contrast enhanced ultrasound (CEUS) could replace CT scans in children with blunt abdominal trauma. CEUS didn't detect as many injuries as CT, so it's not ready to replace CT yet.

Eligible Conditions
  • Traumatic Abdomen

Treatment Effectiveness

Effectiveness Progress

3 of 3
This is further along than 93% of similar trials

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: through study completion, which is expected to take around 3 years

Year 3
Test characteristics of CEUS as compared to gold standard CT

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

1 Treatment Group

Contrast-enhanced ultrasound arm
1 of 1

Experimental Treatment

146 Total Participants · 1 Treatment Group

Primary Treatment: contrast-enhanced ultrasound · No Placebo Group · Phase 4

Contrast-enhanced ultrasound armExperimental Group · 2 Interventions: Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Intravenous Powder for Suspension [LUMASON], contrast-enhanced ultrasound · Intervention Types: Drug, Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: through study completion, which is expected to take around 3 years

Who is running the clinical trial?

Children's Hospital of PhiladelphiaLead Sponsor
651 Previous Clinical Trials
7,849,819 Total Patients Enrolled
Aaron E Chen, MDPrincipal InvestigatorChildren's Hospital of Philadelphia
2 Previous Clinical Trials
328 Total Patients Enrolled

Eligibility Criteria

Age No minimum age - 17 · All Participants · 3 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
patients who received less than 6 units of red blood cells (RBC) in the previous 6 hours did not have an increased incidence of renal failure Some patients who had not received any blood transfusions in the last six hours and were considered to be hemodynamically stable did not experience an increase in renal failure.
for the patient The doctor ordered a CT scan of the patient's abdomen.
warrants a CT scan The text is saying that if a person has a history of or suspicion for blunt abdominal trauma, they should have a CT scan.
References