Isolation Conditions for Stress and Resilience
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you have certain medical conditions or use substances like tobacco, you may not be eligible to participate.
How does the 8-day isolation treatment differ from other treatments for stress and resilience?
The 8-day isolation treatment is unique because it involves placing individuals in a confined space to study stress and resilience, unlike other treatments that might focus on medication or therapy. This approach allows researchers to directly observe the psychological and physiological effects of isolation, which can provide insights into stress management and resilience building.12345
What is the purpose of this trial?
This trial studies how people react to being in a space-like environment, including confinement, work, boredom, and isolation. It aims to find out who can handle the stress of long space missions. Researchers will measure body functions and behaviors to see how well people adapt to these conditions.
Research Team
David Dinges, PhD
Principal Investigator
University of Pennsylvania
Eligibility Criteria
This trial is for English-speaking individuals aged 30-55 with a master's degree or equivalent in STEM or military experience, who are physically and mentally healthy with a BMI under 35. It excludes those with acute medical conditions, major psychiatric illnesses, substance abuse issues, certain cardiovascular/neurological problems, and specific MRI contraindications like metallic implants.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Isolation and Confinement
Subjects will spend 7-night/8-day in an isolated and confined unit with up to 3 other subjects
Follow-up
Participants are monitored for changes in resilience, stress, brain structure and function, sleep, biomarker response to stress, cognitive performance, and heart rate
Treatment Details
Interventions
- 8-Days in an Isolation, Confinement Unit
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Pennsylvania
Lead Sponsor
University of Pittsburgh
Collaborator
National Aeronautics and Space Administration (NASA)
Collaborator