Renal Denervation for High Blood Pressure
(RADIANCE-HTN Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
RADIANCE-HTN is a randomized, double-blind, sham controlled, 2-cohort study (TRIO and SOLO) designed to demonstrate efficacy and document the safety of the Paradise Renal Denervation System in two distinct populations of hypertensive subjects.
Who Is on the Research Team?
Ajay Kirtane, MD
Principal Investigator
Columbia University
Michel Azizi, MD, PhD
Principal Investigator
Hôpital Européen Georges-Pompidou
Are You a Good Fit for This Trial?
This trial is for adults aged 18-75 with high blood pressure who can follow the study plan. Participants must have a history of hypertension and suitable renal anatomy. The SOLO group includes those on blood pressure meds or lifestyle changes, while the TRIO group requires being on at least three different blood pressure medications including a diuretic.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either the sham procedure or renal denervation treatment
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Sham Procedure
- The Paradise® Renal Denervation Ultrasound System
Find a Clinic Near You
Who Is Running the Clinical Trial?
ReCor Medical, Inc.
Lead Sponsor