Treatment for Myocardial Infarction

Phase-Based Estimates
1
Effectiveness
1
Safety
Univeristy of Florida, Gainesville, FL
Myocardial Infarction+1 More
Eligibility
18+
Female
Eligible conditions
Myocardial Infarction

Study Summary

This study is evaluating whether stress management can improve stress levels in women with a history of MI.

See full description

Eligible Conditions

  • Myocardial Infarction
  • Infarction

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome and 4 secondary outcomes in patients with Myocardial Infarction. Measurement will happen over the course of 6 months.

6 months
Patient Health Questionnaire (PHQ-9)
Perceived Stress Scale (PSS-10) scores
Seattle Angina Questionnaire-7 Score (SAQ-7)
Short Form (SF-12) Score
Sleep quality

Trial Safety

Safety Estimate

1 of 3

Trial Design

1 Treatment Groups

Control

This trial requires 200 total participants across 1 different treatment groups

This trial involves a single treatment. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

ControlNo treatment in the control group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 6 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 6 months for reporting.

Closest Location

Univeristy of Florida - Gainesville, FL

Eligibility Criteria

This trial is for female patients aged 18 and older. There are 7 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Female sex
The patient had a PSS-4 score of ≥6 at their 2-month follow-up visit after having a heart attack. show original
, during the preceding 24 hours I have had chest pain or anginal equivalent symptoms at rest or new onset exertional anginal equivalent symptoms in the last 24 hours. show original
is the most common ECG abnormality in patients with acute myocardial infarction The most common ECG abnormality in patients with acute myocardial infarction is ST segment elevation of ≥1mm on 2 contiguous ECG leads. show original
The person is willing to consent to the study and comply with all aspects of the study. show original
The person is over 21 years old. show original
is associated with a sixfold increase in the risk of death The elevation of troponin to above the laboratory upper limit of normal is associated with a sixfold increase in the risk of death. show original

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What causes myocardial infarction?

Add answer

The most important risk factors for MI are known; however, more extensive work is required to investigate the risk factors underlying an individual's risk of developing MI.

Unverified Answer

What are the signs of myocardial infarction?

Add answer

The patient presenting with either chest pain or shortness of breath without cardiac symptoms on examination is unlikely to have STEMI. However, this may be true for a patient presenting with chest pain and cardiac symptoms, who is not on ST-elevation protocol. A routine electrocardiogram in such patients is likely to reveal a heart attack.\n

Unverified Answer

Can myocardial infarction be cured?

Add answer

Myocardial infarction cannot be cured, but with standard medical treatment mortality should be reduced to less than 12.5%. This is a dramatic improvement from the 19.1% mortality in 1936.

Unverified Answer

What is myocardial infarction?

Add answer

STEMI, which is one of the three categories of AMI, is an acute attack of the heart that can cause a heart attack, causing low blood pressure, chest pain, nausea, sweating, breathlessness, and the feeling of fear. This can occur without pain in many cases and most cases are admitted to hospital sooner than the other AMI scenarios and treatment times are often longer as well.

Unverified Answer

How many people get myocardial infarction a year in the United States?

Add answer

The American Heart Association, National Heart Foundation and Cardiovascular Health Association reports that 11 million Americans have a heart attack each year. Around three million more are diagnosed with coronary heart disease (CHD), the leading cause of death in the United States each year.

Unverified Answer

What are common treatments for myocardial infarction?

Add answer

The majority of patients presenting with acute myocardial infarction receive urgent thrombolytic therapy; however, a minority of those undergoing reperfusion therapies do not receive angiography. It is important to recognize the presence and treat patients undergoing catheter procedures as having AMI rather than being excluded from therapy.

Unverified Answer

Does myocardial infarction run in families?

Add answer

Myocardial infarction runs in families. We found no evidence that the common risk locus SNPs are associated with increased risk of first ischemic event. Additional studies to elucidate the aetiology of this disease in families are needed.

Unverified Answer

What does treatment usually treat?

Add answer

The signs and symptoms of chest pain vary and may include a heart attack but the underlying cause is the same. In most of the cases chest pain leads to other diagnoses. Treatment may differ depending on the source of the chest pain and a coronary bypass surgery may be done and other treatment options are also options.

Unverified Answer

Does treatment improve quality of life for those with myocardial infarction?

Add answer

The SF-6D and SF-12D do not appear to provide meaningful information beyond that available from patient interviews and patient-prosthesis mismatch. These instruments should not be employed as substitutes for direct patient-reported tools. Further investigation of QoL instruments is required and research should be undertaken on the use of patient-reported QoL instruments in rehabilitation.

Unverified Answer

What is the average age someone gets myocardial infarction?

Add answer

Since the age profile of MI in the United States is mostly made of healthy individuals aged <65 years, the average age of victims of MI in the United States is about 69 years. This means that the age of an average person who suffers from a myocardial infarction is about 10 years younger than what we think and what doctors think.

Unverified Answer

How does treatment work?

Add answer

Recent findings demonstrates that primary PCI reduces death or MI in individuals with ST elevation MI, as well as MI with no ST elevation and STEMI complicated by either diabetes or renal failure. In contrast to other studies that have found similar improvements in survival with PCI for patients with more severe disease, the absolute survival benefit seen with PCI in patients with the less severe form of STEMI justifies treating all patients aggressively with PCI.

Unverified Answer

Is treatment typically used in combination with any other treatments?

Add answer

Drug combination therapies have not been effective. They have not improved survival rates and have resulted in increased toxicity. Therefore, it is necessary to find medications that are effective alone.

Unverified Answer
See if you qualify for this trial
Get access to this novel treatment for Myocardial Infarction by sharing your contact details with the study coordinator.