Your session is about to expire
← Back to Search
Stem Cell Transplant for Sickle Cell Disease
Study Summary
This trial is looking at a new way to do a stem cell transplant for sickle cell disease. The old way is not working as well as they'd like, so they are trying something new. This study is to see if the new way is better.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- I am between 16 and 60 years old.You are not currently pregnant.I have sickle cell disease with serious complications like stroke, frequent pain, or vision loss.I can care for myself but cannot do normal activities or work.My heart pumps well enough (ejection fraction is 40% or more).My lungs work well enough for treatment (DLCO ≥ 50% predicted).I have a family member who is a partial genetic match for me.My donor relative is not a close enough genetic match for the transplant.I have a sibling who is a complete HLA match and willing to donate stem cells.I am between 16 and 60 years old.I do not have a sibling who is a complete HLA match for me.
- Group 1: Subject treatment
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Approved for 20 Other Conditions - This treatment demonstrated efficacy for 20 other conditions.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is recruiting underway for this research effort?
"Correct. According to the clinicaltrials.gov website, this investigation is still open for enrollment and was initially announced on March 20th 2017. Furthermore, 50 participants are required from 1 site before October 27 2022."
What is the scale of participation in this clinical experiment?
"Affirmative. The information found on clinicaltrials.gov confirms that this experiment is actively enrolling participants, with a post date of March 20th 2017 and an update from October 27th 2022. 50 individuals need to be recruited from 1 medical facility for the study's conclusion."
Is this research open to participants below the age of 85?
"To participate eligibly in this trial, the patient must be between 16 and 60 years of age. Meanwhile, there are 499 trials available for individuals under 18 as well as 868 studies open to seniors aged 65 or older."
What past research has occurred in regards to Stem cell infusion?
"Currently, 1039 investigations related to stem cell infusion are underway with 186 of them in their third phase. Though there is a concentration of trials centered around the city Philadelphia, Pennsylvania, this medical intervention can be accessed at 2920 different sites worldwide."
What conditions are typically remedied through stem cell infusion?
"Stem cell infusion is a common therapeutic approach used to facilitate organ transplants, as well as address immunosuppression, multiple sclerosis, leukemia, myelocytic and acute conditions."
What are the eligibility criteria to partake in this research project?
"This trial, which is recruiting a maximum of 50 participants, requires potential enrollees to be between 16 and 60 years old with anemia or sickle cell."
What risks have been observed with Stem cell infusion treatments?
"The safety of stem cell infusion was evaluated and given a rating of 2 since this is merely a Phase 2 trial with preliminary evidence towards its security but no data on efficacy."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
Share this study with friends
Copy Link
Messenger