AI Triage for Breast Cancer Screening
Trial Summary
What is the purpose of this trial?
One method of breast cancer screening involves radiologists reading digital tomosynthesis (DBT) images. DBT consists of a 3D stack of x-ray "slices" through the breast. The exam is accompanied by a 2D image like a standard mammogram, a single x-ray of the breast. In a screening setting, most cases are normal. Sometimes it is obvious that a case is normal from a quick look at the 2D image. It would speed up the process of screening if readers could dismiss a clearly normal case on the basis of the 2D image, alone, without looking at the DBT images. Obviously, the investigators would only want to "triage" cases in this way if the investigators were almost perfectly sure that no cancers would be missed. In this study, the investigators look at radiologist's willingness to triage cases and on the accuracy of their answers. In addition, the investigators ask about the impact of an Artificial Intelligence (AI) opinion. Would it be possible to triage an image on the basis of the AI opinion, alone?Radiologists will look at each case for up to five seconds and offer an opinion (on a 1-10 scale) about how sure they are that a case is normal. Next, they will see the opinion of the AI. Finally, they will say (using a 1-10) scale, how willing they would be for the AI to triage this case without human intervention.This study is the start of an effort to understand the conditions under which radiologists might be willing to declare a case "normal" with little or no human examination.
Eligibility Criteria
This trial is for radiologists or radiology trainees with experience in reading mammography. Participants must have good vision, at least 20/25 with correction, to be eligible.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Radiologist Evaluation
Radiologists evaluate 2D mammogram images for up to 5 seconds and provide a normality rating. They also assess AI's opinion on the images.
AI Evaluation
AI system evaluates the same images and provides a probability of malignancy score. Radiologists assess the AI's ability to triage cases.
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
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Who Is Running the Clinical Trial?
Brigham and Women's Hospital
Lead Sponsor