Orange flavoured drink for Adults

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Centre for Urban Innovation (CUI-109), School of Nutrition, Ryerson University, Toronto, Canada
Adults+3 More
Orange flavoured drink - Other
Eligibility
18 - 65
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether orange juice can improve satiety and mood in healthy adults.

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Eligible Conditions

  • Adults
  • Glycemic Responses
  • Appetite
  • Healthy Subjects (HS)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether Orange flavoured drink will improve 3 primary outcomes and 4 secondary outcomes in patients with Adults. Measurement will happen over the course of For the rest of the day following test session completion (1 day).

At 60 minutes post-treatment consumption
Ad libitum food intake
Collected at baseline (0 minutes), 15 minutes, 30 minutes, 45 minutes, and 60 minutes post-treatment consumption
Change from baseline glycemic response (acute phase)
Change from baseline subjective appetite
Change from baseline subjective emotions and mood
Hour 24
Rest-of-day blood glucose concentrations
Day 1
Rest-of-the-day food intake
Rest-of-the-day physical activity

Trial Safety

Safety Progress

1 of 3

Trial Design

3 Treatment Groups

Water
1 of 3
Orange flavoured drink
1 of 3
Orange juice
1 of 3
Experimental Treatment

This trial requires 40 total participants across 3 different treatment groups

This trial involves 3 different treatments. Orange Flavoured Drink is the primary treatment being studied. Participants will be divided into 3 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Water
Other
Treatment beverage
Orange flavoured drink
Other
Treatment beverage
Orange juice
Other
Treatment beverage

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: collected at baseline (0 minutes), 15 minutes, 30 minutes, 45 minutes, and 60 minutes post-treatment consumption
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly collected at baseline (0 minutes), 15 minutes, 30 minutes, 45 minutes, and 60 minutes post-treatment consumption for reporting.

Who is running the study

Principal Investigator
N. B.
Prof. Nick Bellissimo, Associate Professor
Ryerson University

Closest Location

Centre for Urban Innovation (CUI-109), School of Nutrition, Ryerson University - Toronto, Canada

Eligibility Criteria

This trial is for patients born any sex between 18 and 65 years old. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
aged 18-45 years;
Adults with a BMI within the healthy range (18.5-24.9 kg/m2) are less likely to experience health problems. show original

Patient Q&A Section

What is healthy subjects (hs)?

"Healthy subjects are commonly used as an important tool for quality, cost saving measures, and in the design of large RCTs. This practice is not without weaknesses. A clearer definition of what constitutes healthy subjects and its use during clinical research and practice are required." - Anonymous Online Contributor

Unverified Answer

Can healthy subjects (hs) be cured?

"The positive results were highly encouraging for a cure of hs; thus they might be candidates to try the treatment before proceeding to clinical trials. The absence of any side-effects in hs is particularly important. The potential of the new immunotherapy for other immunocompromised patients that may be cured with the same treatment, for example, HIV or cancer, is intriguing and further studies are warranted." - Anonymous Online Contributor

Unverified Answer

How many people get healthy subjects (hs) a year in the United States?

"Over 250,000 healthy volunteers and 3,500 subjects with chronic, unexplained respiratory disease are being tested a year in the United States. The incidence of asymptomatic, chronic, persistent respiratory disease is 4.3 per 1,000 persons tested." - Anonymous Online Contributor

Unverified Answer

What are common treatments for healthy subjects (hs)?

"Common treatments for healthy subjects (hs) are usually nonspecific, with many treatments being given to every subject. These include nutrition, exercise, and a range of relaxation therapies. There is no evidence of the effectiveness of vitamins and/or herbal supplements for healthy subjects.\n" - Anonymous Online Contributor

Unverified Answer

What causes healthy subjects (hs)?

"In our population of healthy subjects, there were no significant differences between men and women in terms of age but some differences regarding physical activity with the lowest levels for men." - Anonymous Online Contributor

Unverified Answer

What are the signs of healthy subjects (hs)?

"Healthy controls show typical fluctuations in body temperature and heart rate at rest. The variability is similar in hs and hc, but higher in hc. The relationship between heart rate variability and body temperature indicates reduced efficiency of the autonomic heat preservation system in hc." - Anonymous Online Contributor

Unverified Answer

What is the primary cause of healthy subjects (hs)?

"Recent findings reveals that the most common causes of hs are age >/= 50 and hs that are part of regular screening programmes. The most common causes for infertility are female hypothyroidism, ovarian dysfunction, and male hypogonadism." - Anonymous Online Contributor

Unverified Answer

What is the latest research for healthy subjects (hs)?

"Using [clinicaltrials.gov/ct2>; a website for tracking clinical trials, you can find which clinical trials are underway where healthy subjects are being used. Most of the trials you'll find have no mention of healthy subjects, so it is best to ask for them at the trial's site directly. If you want to see the latest healthy subjects research, you can find it by searching for an article on the site [clinicaltrials.gov/ct2/]. For that site, you can also find the latest clinical trials in the area where you reside." - Anonymous Online Contributor

Unverified Answer

Does healthy subjects (hs) run in families?

"Recent findings indicates that a common genetic basis may account for the shared phenotype among children and their siblings of the same family. This suggests that gene-environment interactions play critical roles in childrens' development." - Anonymous Online Contributor

Unverified Answer

How serious can healthy subjects (hs) be?

"The risk that healthy subjects (hs) may have an adverse outcome during or following an upper gastrointestinal endoscopy is minimal, low, and the risk of serious harm is very small. This risk may be further reduced by performing a routine preendoscopy blood laboratory study and by obtaining a detailed medical history from patients." - Anonymous Online Contributor

Unverified Answer

Has orange flavoured drink proven to be more effective than a placebo?

"Orange flavoured drinks containing 100 mg/l anthocyanin are at least as effective as a placebo from a functional point of view (both objectively and subjectively). Since there is no evidence that flavoured drink intake (both flavoured drink and flavoured water) improves the functional status and/or the global QOL, the actual benefits from orange flavoured drinks on health are limited." - Anonymous Online Contributor

Unverified Answer

Is orange flavoured drink safe for people?

"The data suggest an association between intake of orange flavoured drink and elevated serum creatinine, and thus an increased risk of developing hyperuricaemia in men. Further studies are recommended to assess how these findings relate to changes in serum creatinine levels in the longer term." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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