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Hormone Therapy

Insulin Therapy After Cardiac Surgery

N/A

Waitlist Available

Led By Roupen Hatzakorzian, MD

Research Sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up eight hours after the end of surgery

Awards & highlights

Study Summary

This trial will investigate the effect of high-dose insulin therapy on protein, glucose, and end-organ metabolism in patients undergoing CABG surgery.

Who is the study for?

This trial is for patients who can consent and are undergoing elective cardiac surgery, specifically CABG. It's not suitable for those with severe malnutrition or obesity (BMI <20 or >30), significant weight loss in the past six months, or chronic liver failure.Check my eligibility

What is being tested?

The study tests high-dose insulin therapy on protein and glucose metabolism during CABG surgery. Patients will be split into two groups: one receiving standard insulin to keep blood sugar under control, and another getting a high dose of insulin plus glucose to maintain normal blood sugar levels.See study design

What are the potential side effects?

While specific side effects aren't listed, potential risks may include low blood sugar due to high-dose insulin therapy, which could cause shakiness, sweating, confusion, heart palpitations or even loss of consciousness if severe.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ eight hours after the end of surgery

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~eight hours after the end of surgery

This trial's timeline: 3 weeks for screening, Varies for treatment, and eight hours after the end of surgery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Protein breakdown

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: High-dose insulinExperimental Treatment1 Intervention

Group II: ControlActive Control1 Intervention

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

McGill University Health Centre/Research Institute of the McGill University Health CentreLead Sponsor

442 Previous Clinical Trials

159,144 Total Patients Enrolled

Roupen Hatzakorzian, MDPrincipal InvestigatorMcGill University Health Centre/Research Institute of the McGill University Health Centre

Media Library

Regular human insulin injection (Hormone Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT01601561 — N/A

Cardiac Surgery Research Study Groups: High-dose insulin, Control

Cardiac Surgery Clinical Trial 2023: Regular human insulin injection Highlights & Side Effects. Trial Name: NCT01601561 — N/A

Regular human insulin injection (Hormone Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01601561 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I qualified to participate in this medical research?

"This trial is open to patients that have experienced cardiac surgery, who are between the ages of 18 and 90. In total, 30 participants will be accepted into this medical study."

Answered by AI

Are there any available opportunities for individuals to become participants in this study?

"This clinical trial has ceased recruitment, with its latest edit on 5/17/2012. Should you be looking for other medical studies, 47 trials are currently searching for participants related to surgery or cardiac care and 72 involve the injection of regular human insulin."

Answered by AI

Has previous research involved the usage of Regular human insulin injections?

"At present, there are 72 open clinical tests examining Regular human insulin injection with 13 trials in the last phase. The majority of these studies occur in Cincinnati, Ohio but other regions have been identified where this treatment is being studied. In total, 248 locations offer clinical trial for Regular human insulin injection."

Answered by AI

Is the enrollment process open to individuals aged thirty-five and older?

"According to the criteria for acceptance into this trial, it is open to any individual aged 18 or higher and below 90."

Answered by AI

What is the cap for participants in this clinical trial?

"This clinical trial is no longer accepting participants. As per the information on clinicaltrials.gov, it was first posted in June 2010 and last updated May 2012. For those looking for other studies, there are currently 47 trials that involve surgery or cardiac procedures enrolling candidates as well as 72 medical studies involving Regular Human Insulin Injection actively recruiting patients."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

The Effect of Insulin on Protein Metabolism After Cardiac Surgery

2010. "The Effect of Insulin on Protein Metabolism After Cardiac Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01601561.

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