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Behavioral Intervention

Preventure programme for Alcohol Use Disorder

Waitlist Available
Research Sponsored by St. Justine's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up years 1, 2, 3,4 and 5
Awards & highlights


The Preventure Program is the first and only school-based alcohol and drug prevention program that has been shown to prevent onset and growth in alcohol and substance misuse in British and Canadian youth. Unlike universal programs that tend to promote generic coping skills and balance normative attitudes around substance use, this selected personality-targeted approach is based on a psychosocial model and validated by Dr Patricia Conrod and targets four personality-specific motivational pathways to substance misuse: Hopelessness, Anxiety Sensitivity, Impulsivity and Sensation Seeking, each associated with different motives for substance use, drug use profiles and patterns of non-addictive psychopathology. As a primary goal of the Coventure project, the investigators propose a long-term trial of this intervention strategy to examine how this evidence-based intervention can reduce onset of substance use disorders in young people and related secondary mental health, academic and cognitive outcomes. As a secondary goal, the investigators propose to use sensitive neuropsychological measures to examine how this evidence-based intervention can positively impact on cognitive development over the course of adolescence, to tease apart some of the mechanisms involved in the causal pathway from early onset substance use to poor cognitive development and long-term addiction outcomes.

Eligible Conditions
  • Alcohol Use Disorder
  • Substance Use Disorders


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~years 1, 2, 3,4 and 5
This trial's timeline: 3 weeks for screening, Varies for treatment, and years 1, 2, 3,4 and 5 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Dep Ado: onset, frequency and binge items
Secondary outcome measures
Executive function
Functional cognitive measures
Global cognitive function
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Preventure programmeExperimental Treatment1 Intervention
The interventions are conducted using manuals which incorporate psycho-educational, motivational enhancement therapy and cognitive-behavioural (CBT) components, and include real life 'scenarios' shared by local youth in with similar personality profiles. In the first session, participants are guided in a goal-setting exercise, designed to enhance motivation to change behaviour. Psycho-educational strategies are then used to teach participants about the target personality variable and associated problematic coping behaviours like avoidance, interpersonal dependence, aggression, risky behaviours and substance misuse.

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Who is running the clinical trial?

Canadian Institutes of Health Research (CIHR)OTHER_GOV
1,354 Previous Clinical Trials
26,460,488 Total Patients Enrolled
St. Justine's HospitalLead Sponsor
196 Previous Clinical Trials
79,311 Total Patients Enrolled
Patricia J Conrod, PhDStudy ChairUniversité de Montréal
3 Previous Clinical Trials
7,252 Total Patients Enrolled
~2 spots leftby Jul 2025