Reviewed by Michael Gill, B. Sc.
1 Genital Warts Clinical Trials Near Me
Top Hospitals for Genital Warts Clinical Trials
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Zuckerberg San Francisco General Hospital
San Francisco
1Active Trials
0All Time Trials for Genital Warts
2022First Genital Warts Trial
Top Cities for Genital Warts Clinical Trials
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San Francisco
1Active Trials
Zuckerberg San Francisco General HospitalTop Active Site
Genital Warts Clinical Trials by Phase of Trial
Phase 1 & 2 Genital Warts Clinical Trials
1Active Genital Warts Clinical Trials
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18+ Genital Warts Clinical Trials
1Active Genital Warts Clinical Trials
Most Recent Genital Warts Clinical Trials
Clinical Trial
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Top Treatments for Genital Warts Clinical Trials
Treatment Name
Active Genital Warts Clinical Trials
All Time Trials for Genital Warts
First Recorded Genital Warts Trial
nonavalent human papillomavirus vaccine

What Are Genital Warts Clinical Trials?

Genital warts are the most common of all STIs, according to the CDC. These appear as soft growths on the genitals. These warts form because of Human Papillomavirus (HPV)'s low strains, including HPV 11 and HPV 6. Genital warts cause itching, discomfort, and pain.

The HPV infection is more dangerous for individuals with vulvas since high-risk stains could result in cancer of the vulva and cervix.

Why Are Genital Warts Being Studied Through Clinical Trials?

Before the introduction of HPV vaccinations, genital warts annually impacted around 340,000 to 360,000 individuals. This translates to one in every 100 sexually active individuals.

Genital infections, including genital warts, have a prevalence of about 10% to 20%. Moreover, 80% of infected individuals are aged between 17 years and 33 years.

The major risk factors for genital warts and other HPV include immunosuppression, smoking, age, and infections with various HPV types.

What Are The Types of Treatments Available For Genital Warts?

There are multiple treatments available for genital warts, but a dermatologist can determine the right one based on multiple factors, including the location of warts, the number of warts, and the physical health of the patient.

The treatment could include medication or a procedure. Some of the significant medications prescribed for genital warts include:

  • Sinecatechins (green tea extract) ointment for warts near the anus and external warts
  • Imiquimod, which enhances the immune system of the body to fight HPV
  • Podofilox to prevent the growth of wart cells for external warts

Some of the procedures to treat genital warts include:

  • Cryotherapy
  • Electrocautery
  • Surgical excision
  • Laser treatment

What Are Some Recent Breakthrough Clinical Trials For Genital Warts?

There have been several landmark studies involving genital warts in recent years. Some of the most recent studies are:

2021: A new research revealed the connection between the human leukocyte antigen (HLA) system and genital warts. The results indicate the genetic variants present in the HLA can have an impact on the risk of developing genital warts. This is a breakthrough that can help in producing an effective mRNA vaccine for genital warts.

2020: Verrica Pharmaceuticals found promising results during the Phase 2 CARE-1 VP-102 clinical study, which is a topical therapy using 0.7% cantharidin solution for the treatment of external genital warts in a single-use applicator. The VP-102 attained positive results in the primary and secondary endpoint of complete clearance and reduction of genital warts. The breakthrough results indicate that VP-102 can be given to patients with an effective and well-tolerated treatment option for genital warts.

Who Are Some Of The Key Opinion Leaders / Researchers / Institutions Conducting Genital Warts Clinical Trials Research?

Merck Sharp & Dohme LLC is a global healthcare organization that is dedicated to funding clinical trials to find innovative solutions to health disorders, including genital warts, by finding the best prescription medicines, biological therapies, vaccines, and other health products.

Tamir Biotechnology is a biopharmaceutical organization that engages and funds the development and discovery of therapeutic drugs for cancer treatment and HPV treatment, including genital warts.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 23rd, 2021

Last Reviewed: October 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.