Genetic Testing for Cancer Risk

Recruiting at 1 trial location

Overseen By Clinical Trials Referral Office

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Mayo Clinic

Disqualifiers: Hematological cancer, Bone marrow transplants, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

1800 Participants Needed

Trial Summary

What is the purpose of this trial?

This clinical trial examines the integration of cancer genetic testing in various ethnic populations. Studying individuals and families at risk of cancer may help identify cancer genes and other persons at risk. The information from this study may provide an opportunity for cancer risk stratification and individualized screening in these ethnic populations.

Research Team

Jewel Samadder, M.D.

Principal Investigator

Mayo Clinic

Eligibility Criteria

This trial is for adults from diverse ethnic backgrounds, including Hispanic/Latino, Native American/Alaskan, African American, Asian and European descent who have solid tumor cancers. They must be able to provide a blood sample and agree to genetic testing at Mayo Clinic in Arizona or Florida.

Inclusion Criteria

You are from certain ethnic backgrounds such as Hispanic/Latino, Native American/Alaskan, African American, Asian, and other European populations.

I have been diagnosed with a solid tumor cancer and am seeking treatment at Mayo Clinic.

I can safely provide the needed blood samples.

Exclusion Criteria

I had a genetic test with 40+ genes at Mayo Clinic in the last 2 years, and the results can be reviewed.

I have or had blood cancer, like leukemia or multiple myeloma.

I have had a bone marrow transplant.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Biospecimen Collection

Patients undergo collection of blood or saliva sample for genetic testing

1 week

1 visit (in-person)

Follow-up

Participants are monitored for the impact of genetic testing on therapeutic management and targeted cancer prevention

2 years

Treatment Details

Interventions

• Cancer Genetic Testing

Trial Overview The study focuses on collecting biospecimens and conducting genetic tests among various ethnic groups. It aims to identify cancer genes for better risk assessment and personalized screening strategies.

Participant Groups

Group I: Screening (biospecimen collection) Experimental Treatment 2 Interventions

Patients undergo collection of blood or saliva sample for genetic testing.

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials

3,427

Recruited

3,221,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+