Intervention Strategies for Increasing HPV Vaccination Rates
(HPV MISTICS Trial)
Trial Summary
Do I need to stop my current medications to join the trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the HPV vaccine treatment?
The 9-valent HPV vaccine (9vHPV), known as Gardasil 9, has shown high effectiveness in preventing cervical, vulvar, and vaginal precancers caused by HPV types, with over 90% efficacy in clinical studies. It also offers protection against additional cancer-causing HPV types, potentially preventing up to 93% of cervical cancer cases and a significant proportion of other HPV-related cancers.12345
Is the HPV vaccine safe for humans?
How does this treatment increase HPV vaccination rates?
This treatment is unique because it focuses on strategies like starting HPV vaccination at age 9 during well-child visits, using reminders, education, and scheduling future appointments to ensure vaccine completion. It also involves integrating the HPV vaccine with other adolescent vaccines and using strong provider recommendations to improve vaccination rates.1112131415
What is the purpose of this trial?
This intervention study will use parent-, provider-, and health center-level strategies to promote HPV vaccination among 11-17 year olds receiving care in 8 community health centers in Florida, will explore factors related to the intervention effect, and will explore implementation outcomes of the intervention.
Research Team
Susan T Vadaparampil, PhD, MPH
Principal Investigator
Moffitt Cancer Center
Shannon Christy, PhD
Principal Investigator
Moffitt Cancer Center
Eligibility Criteria
This trial is for English or Spanish-speaking parents of 11-17 year olds, healthcare providers, and staff at certain health centers in Florida. It's focused on those who have not started or completed the HPV vaccine series. Participants must be over 18 and interact with parents of adolescents who are eligible for the HPV vaccine.Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Implementation of parent-, provider-, and health center-level strategies to promote HPV vaccination
Follow-up
Participants are monitored for HPV vaccine initiation and completion rates, and implementation outcomes
Treatment Details
Interventions
- HPV MISTICS- HPV Vaccine Champion Level
- HPV MISTICS - Parent Level
- HPV MISTICS -Provider Level
Find a Clinic Near You
Who Is Running the Clinical Trial?
H. Lee Moffitt Cancer Center and Research Institute
Lead Sponsor
Florida Department of Health
Collaborator
Health Choice Network
Collaborator