Verified
LSD derivative

Arm 3- 50 μg MM-120 (LSD D-Tartrate) for Generalized Anxiety Disorder

IPS Research, Oklahoma City, OK
MM-120 (LSD D-Tartrate) +1 morePhase 2RecruitingResearch Sponsored by Mind Medicine, Inc.

Study Summary

This trial will test if MM-120 can effectively treat symptoms of generalized anxiety disorder. The trial will have 4 groups who will each receive a different dose of MM-120.

Eligible Conditions
  • Generalized Anxiety Disorder

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below
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You are able to swallow pills.
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You have been diagnosed with a specific type of anxiety disorder called DSM-5 generalized anxiety disorder.

Timeline

Screening ~ 1 day
Treatment ~ Varies
Follow Up ~6 weeks
This trial's timeline: 1 day for screening, Varies for treatment, and 6 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Assess the incidence of Adverse Events (AEs) and Serious Adverse Events (AEs)
Dose-Response
Improved Quality of Life as measured by EuroQol 5 Dimension 5 Level (EQ-5D-5L)

Trial Design

5Treatment groups
Experimental Treatment
Placebo Group
Group I: Arm 5- 200 μg MM-120 (LSD D-Tartrate)Experimental Treatment1 Intervention
A psychoactive substance that mediates effects mainly through an agonist activity in the serotonin 2A receptor (5-HT2A).
Group II: Arm 4- 100 μg MM-120 (LSD D-Tartrate)Experimental Treatment1 Intervention
A psychoactive substance that mediates effects mainly through an agonist activity in the serotonin 2A receptor (5-HT2A).
Group III: Arm 3- 50 μg MM-120 (LSD D-Tartrate)Experimental Treatment1 Intervention
A psychoactive substance that mediates effects mainly through an agonist activity in the serotonin 2A receptor (5-HT2A).
Group IV: Arm 2- 25 μg MM-120 (LSD D-Tartrate)Experimental Treatment1 Intervention
A psychoactive substance that mediates effects mainly through an agonist activity in the serotonin 2A receptor (5-HT2A).
Group V: Arm 1- PlaceboPlacebo Group1 Intervention
A substance that is designed to have no therapeutic value.

Find a site

Logistics

Other reimbursement is provided

Other forms of reimbursement are provided for this trial.

Who is running the clinical trial?

Mind Medicine, Inc.Lead Sponsor
3 Previous Clinical Trials
560 Total Patients Enrolled

Media Library

MM-120 (LSD derivative) Clinical Trial Eligibility Overview. Trial Name: NCT05407064 — Phase 2
Generalized Anxiety Disorder Research Study Groups: Arm 3- 50 μg MM-120 (LSD D-Tartrate), Arm 1- Placebo, Arm 5- 200 μg MM-120 (LSD D-Tartrate), Arm 2- 25 μg MM-120 (LSD D-Tartrate), Arm 4- 100 μg MM-120 (LSD D-Tartrate)
Generalized Anxiety Disorder Clinical Trial 2023: MM-120 Highlights & Side Effects. Trial Name: NCT05407064 — Phase 2
MM-120 (LSD derivative) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05407064 — Phase 2
Generalized Anxiety Disorder Patient Testimony for trial: Trial Name: NCT05407064 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are recruitment efforts still active for this trial?

"Affirmative. According to information posted on clinicaltrials.gov, this trial is currently seeking participants since its inception on August 27th 2022 and as recently as November 17th 2022. The research requires 200 patients across 15 different sites for completion."

Answered by AI

Has the Federal Drug Administration authorized MM-120 as a safe and effective treatment?

"MM-120's safety rating was assessed at 2, as it is currently in its second phase of clinical trials with limited data supporting efficacy."

Answered by AI

How many sites are hosting this clinical investigation?

"This clinical trial is welcoming patients to participate at BioBehavioral Research of Austin in Austin, Texas; Hassman Research Institute in Berlin, New Jersey; Irvine Center for Clinical Research in Irvine, California; and an additional 15 medical centres."

Answered by AI

How many individuals have been admitted to the research project?

"To successfully complete this clinical trial, 200 qualified patients are needed. To find a location near them, participants can turn to BioBehavioral Research of Austin in Texas or Hassman Research Institute in New Jersey."

Answered by AI

Is there an opportunity to participate in this exploration?

"This clinical trial requires 200 participants who suffer from DSM-5 Generalized Anxiety Disorder, are between 18 and 74 years old, have a bodyweight of 50kg or more and an acceptable Body Mass Index (BMI) ranging from 18 to 38 mg/kg2. Additionally, they must be able to swallow capsules, provide informed consent and possess sound medical health in order to safely join the study."

Answered by AI

Does the upper age limit for this medical trial extend beyond thirty years of age?

"This medical trial has an age criterion that requires all participants to be at least 18 years old and no older than 74."

Answered by AI

Who else is applying?

What state do they live in?
California
New York
Other
Florida
How old are they?
18 - 65
What site did they apply to?
Pacific Neuroscience Institute
Nautilus Sanctuary
Other
Segal Trials
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
2
1
0
3+

Why did patients apply to this trial?

I tried many things. Looking for something that works. Traditional medicine hasn’t seemed to help.
Patient
I’ve been on meds, TMS and hospitalizations. Because I am wanting to no longer use medication.
Patient

What questions have other patients asked about this trial?

How invasive is the trial? How often would I come to see you? How many visits does this require?
Patient
Do I have to stop taking my medication?
Patient

How responsive is this trial?

Typically responds via
Email
Phone Call
Most responsive sites:
  1. Segal Trials: < 24 hours
  2. BioBehavioral Research of Austin: < 24 hours
Average response time
  • < 1 Day
~100 spots leftby Sep 2024