Your session is about to expire
← Back to Search
Surgery
Retroperitoneal Lymph Node Dissection for Testicular Seminoma
N/A
Waitlist Available
Led By Siamak Daneshmand
Research Sponsored by University of Southern California
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Axial imaging of lymphadenopathy within 6 weeks of the date of RPLND
Biopsy is not required, though if biopsy of the retroperitoneal node(s) was obtained, pathology must be consistent with pure seminoma
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
Study Summary
This trial studies how well a surgery to remove lymph nodes in the retroperitoneum works in treating patients with early-stage testicular seminoma.
Who is the study for?
This trial is for patients with stage I-IIa testicular seminoma who've had an orchiectomy and show signs of cancer spread to lymph nodes in the retroperitoneum. Eligible participants should not have received prior chemotherapy or radiotherapy, must be within three years of initial diagnosis, and have good overall health as indicated by ECOG status.Check my eligibility
What is being tested?
The study is testing the effectiveness of Retroperitoneal Lymph Node Dissection (RPLND) surgery in treating testicular seminoma that has potentially spread to abdominal lymph nodes. The goal is to see if this procedure can reduce long-term health issues like second cancers or heart disease.See study design
What are the potential side effects?
While specific side effects are not listed, RPLND surgery may include risks such as bleeding, infection, damage to surrounding organs, possible changes in fertility and complications from anesthesia.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I had imaging of my lymph nodes done within the last 6 weeks.
Select...
If I had a biopsy, it showed pure seminoma.
Select...
I can carry out all my self-care but cannot do heavy physical work.
Select...
I have 1 to 2 swollen lymph nodes in my abdomen, each less than 3 cm.
Select...
My lymph node swelling is within the surgical area for RPLND.
Select...
My testicular cancer was removed and confirmed as pure seminoma.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 5 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Secondary outcome measures
Long-term RPLND complication rates
RFS
Short-term RPLND complication rates
Trial Design
1Treatment groups
Experimental Treatment
Group I: Treatment (RPLND)Experimental Treatment2 Interventions
Patients undergo RPLND.
Find a Location
Who is running the clinical trial?
National Cancer Institute (NCI)NIH
13,654 Previous Clinical Trials
40,933,098 Total Patients Enrolled
7 Trials studying Lymphadenopathy
370 Patients Enrolled for Lymphadenopathy
University of Southern CaliforniaLead Sponsor
905 Previous Clinical Trials
1,596,263 Total Patients Enrolled
1 Trials studying Lymphadenopathy
13 Patients Enrolled for Lymphadenopathy
Siamak DaneshmandPrincipal InvestigatorUniversity of Southern California
1 Previous Clinical Trials
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- If I had a biopsy, it showed pure seminoma.My recent chest scans show no signs of cancer spread.I do not have any serious illnesses or social situations that would stop me from following the study's requirements.I can carry out all my self-care but cannot do heavy physical work.My blood clotting tests are suitable for surgery, as determined by my surgeon.I have had chemotherapy or radiotherapy in the past.I had imaging of my lymph nodes done within the last 6 weeks.I have 1 to 2 swollen lymph nodes in my abdomen, each less than 3 cm.My lymph node grew to 1.0 cm or more after a borderline CT scan result.I have a type of testicular cancer that has spread to my abdomen lymph nodes or returned there within 3 years.My lymph node swelling is within the surgical area for RPLND.My testicular cancer was removed and confirmed as pure seminoma.I have been diagnosed with more than one type of cancer.
Research Study Groups:
This trial has the following groups:- Group 1: Treatment (RPLND)
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How widely dispersed are the facilities conducting this examination within this state?
"There are 14 locations hosting this clinical trial, including the Rutgers Cancer Institute of New jersey in New Brunswick, University of California, San Francisco in San Francisco and Loma Linda University Medical Center in Loma Linda. In addition to these sites, there is a host of other centres available for patient enrolment."
Answered by AI
Is there still availability for individuals to enroll in this clinical investigation?
"According to clinicaltrials.gov, this medical investigation is not currently recruiting participants. Initially posted on August 28th 2015 and updated lastly on August 6th 2022, the trial has yet to accept any patients. Nevertheless, there are presently 28 other trials actively searching for volunteers."
Answered by AI
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger