Study Summary
This trial will study how much ascorbic acid (AA) the body produces and how it affects the amount of oxalate in urine.
Eligible Conditions
- Kidney Stones
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 0 Secondary · Reporting Duration: Day 4
Day 4
Percent contribution of ascorbic acid (AA) to urinary oxalate excretion
Trial Safety
Safety Progress
Trial Design
1 Treatment Group
Controlled Dietary Study
1 of 1
Experimental Treatment
136 Total Participants · 1 Treatment Group
Primary Treatment: Carbon-13 Ascorbic Acid Oral Load · No Placebo Group · N/A
Controlled Dietary StudyExperimental Group · 2 Interventions: Carbon-13 Ascorbic Acid Oral Load, Low Oxalate Diet · Intervention Types: DietarySupplement, DietarySupplement
Trial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: day 4
Who is running the clinical trial?
University of Alabama at BirminghamLead Sponsor
1,437 Previous Clinical Trials
2,229,208 Total Patients Enrolled
11 Trials studying Kidney Stones
636 Patients Enrolled for Kidney Stones
John Knight, PhDPrincipal InvestigatorUniversity of Alabama at Birmingham
1 Previous Clinical Trials
20 Total Patients Enrolled
Eligibility Criteria
Age 19 - 75 · All Participants · 10 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:For stone formers: composition of most recent stone > 50% calcium oxalate, no uric acid component.
You are willing to stop taking supplements for 2 weeks before start and during study.
You are willing to ingest menus prepared in Clinical Research Unit at University of Alabama at Birmingham.
You have no food allergies or intolerance to any of the foods in study menus.
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Conditions
Cancer Related
Treatments