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Phenylephrine for Blood Loss in Burn Surgery
Study Summary
This trial will compare the effects of epinephrine and phenylephrine solutions on blood loss during skin grafting in burn patients.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I need surgery for a burn covering 5-30% of my body.I am currently taking a Beta-blocker medication.I have a history of high blood pressure.I have a history of heart or blood vessel disease.I have a history of irregular heartbeats.I have a history of blood vessel problems.I have burns on my head, neck, hands, feet, or genital areas.I am currently taking blood thinners.I am currently taking a monoamine oxidase inhibitor or tricyclic antidepressant.
- Group 1: Phenylephrine
- Group 2: Epinephrine
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
For what medical conditions is Phenylephrine typically prescribed?
"Phenylephrine is typically prescribed to alleviate bronchial blockage. It can also provide relief from conditions like sinus congestion, allergic rhinitis, and ocular inflammation."
Is it possible to enroll in this investigation at the present time?
"Affirmative. Information hosted on clinicaltrials.gov confirms that this medical investigation, which was first posted on December 1st 2014, is seeking volunteers. This project requires 24 participants to be recruited from a single site."
How many applicants are being granted admittance to this experiment?
"Affirmative. According to information held on clinicaltrials.gov, this research programme is still recruiting volunteers, having first been posted on December 1st 2014 and last edited November 1st 2022. 24 people are being sought from a single medical site."
Are there any precedents for scientific research into Phenylephrine?
"Currently, 26 clinical trials are in progress to evaluate the effects of Phenylephrine. Of these studies, 5 have entered Phase 3. Moreover, 37 different sites across America are hosting experiments with this drug; a major contribution is being made by New Haven CT."
Has Phenylephrine been confirmed by the FDA?
"The lack of clinical data regarding Phenylephrine's safety and efficacy resulted in it receiving a score of 1."
Am I able to register for this research endeavor?
"Candidates seeking admission to this trial should have a history of blood loss, surgical intervention and be between 18 to 75 years old. This study is expecting around 24 participants in total."
Are octogenarians permissible to participate in this clinical research?
"To be eligible for this trial, participants must range from 18 to 75 years of age. Alternatively, there are 59 studies available for minors and 308 investigations dedicated to individuals above the retirement age bracket."
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