Fruit Consumption for Gut Health
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how varying fruit intake affects gut health and overall well-being. It examines the impact of fruit on gut bacteria, heart health, brain function, and movement control. Participants will consume either two cups of fruit per day or limit themselves to a half-cup. Ideal candidates are healthy individuals aged 30 to 70 without a history of serious health conditions such as strokes, heart attacks, or certain chronic disorders. As an unphased trial, this study allows participants to contribute to groundbreaking research on diet and health.
Do I need to stop taking my current medications for the trial?
The trial requires that you do not take medications for lipid reduction, hypertension, or psychiatric conditions. If you are on these medications, you would need to stop taking them to participate.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
A previous study found that adults should eat about 1.5 to 2 cups of fruit each day as part of a healthy diet. Research has shown that fruits provide dietary fiber, which can help lower the risk of heart disease and obesity. Fruits are generally low in calories and are a good source of fiber and potassium. Thus, eating 2 cups of fruit per day is safe and beneficial for most people.
Participants in the group with a fruit restriction will eat 1/2 cup of fruit per day. Although this is less than the recommended daily amount, it remains safe. There are no specific safety concerns for either group, as both involve eating fruit, a normal part of a healthy diet.12345Why are researchers excited about this trial?
Researchers are excited about exploring fruit consumption for gut health because it taps into the potential of natural, dietary adjustments rather than relying on medications or supplements. Unlike common treatments that might focus on probiotics or fiber supplements, this approach utilizes whole fruits, providing a rich source of vitamins, antioxidants, and fiber in a natural form. The trial is examining two different levels of fruit intake, which could offer insights into how varying quantities affect gut health, potentially paving the way for personalized dietary recommendations. This method emphasizes simplicity and accessibility, aiming to improve gut health through everyday food choices.
What evidence suggests that this trial's treatments could be effective for gut health?
Studies have shown that eating fruits can improve heart health, brain function, and movement skills. For example, consuming 2 cups of fruit daily has been linked to better weight control, especially in women. In this trial, one group of participants will receive 2 cups of fruit per day to assess these potential benefits. However, some research has also found that this amount doesn't change certain heart health measures or improve brain and body balance in the short term. Another group in this trial will receive 1/2 cup of fruit per day to compare the effects. Overall, fruits are known to be beneficial for health, but the specific effects can vary.36789
Are You a Good Fit for This Trial?
This trial is for healthy men and women aged 30 to 70. It's not suitable for those with gastrointestinal, metabolic, or neurological disorders, a history of stroke or heart attack, or anyone on psychiatric meds or drugs for lipid reduction/hypertension.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants consume either 2 cup eq fruits per day or 1/2 cup eq fruits per day to assess the impact on gut microbiota and health outcomes
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Fruit (2 cup eq)
- Fruit restriction (1/2 cup eq)
Find a Clinic Near You
Who Is Running the Clinical Trial?
San Diego State University
Lead Sponsor