AF Education for Atrial Fibrillation

Phase-Based Estimates
1
Effectiveness
1
Safety
Stanford Health Care, Stanford, CA
Atrial Fibrillation+1 More
AF Education - Other
Eligibility
18+
All Sexes
Eligible conditions
Atrial Fibrillation

Study Summary

This study is evaluating whether a combination of mindfulness meditation, education about atrial fibrillation, and weekly phone calls may help improve quality of life and reduce symptoms for individuals with atrial f

See full description

Eligible Conditions

  • Atrial Fibrillation
  • Paroxysmal Atrial Fibrillation (PAF)

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Compared to trials

Study Objectives

This trial is evaluating whether AF Education will improve 2 primary outcomes and 1 secondary outcome in patients with Atrial Fibrillation. Measurement will happen over the course of Baseline (Initial), 12 months.

Baseline (Initial), 12 month
Change from Baseline Atrial Fibrillation Symptom Burden and Symptom Severity Scores
Change from Baseline in AF Quality of Life Score
Baseline (Initial), 12 months
Change from Baseline in Anxiety

Trial Safety

Safety Estimate

1 of 3

Compared to trials

Trial Design

7 Treatment Groups

No Control Group
Mindfulness Meditation Practice

This trial requires 75 total participants across 7 different treatment groups

This trial involves 7 different treatments. AF Education is the primary treatment being studied. Participants will be divided into 7 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Mindfulness Meditation Practice
Behavioral
Each participant watches an mindfulness meditation introductory video in the initial session and then is asked to practice for 10 minutes each day using a guided audio, which includes a different topic each week. The time duration of the guided meditations increases to 15 minutes each day during Weeks 3-6.
AF Education and Mindfulness MeditationParticipant receives 6 modules of AF education topics that are intended to be completed consecutively, one each week. Each participant watches an mindfulness meditation introductory video in the initial session and then is asked to practice for 10 minutes each day using a guided audio, which includes a different topic each week. The time duration of the guided meditations increases to 15 minutes each day during Weeks 3-6.
AF education
Other
Participant receives 6 modules of AF education topics that are intended to be completed consecutively, one each week.
AF Education and Weekly Phone CallsParticipant receives 6 modules of AF education topics that are intended to be completed consecutively, one each week. Each week for the six-week intervention, the researcher will contact the participant by phone at an agreed upon time and will discuss any questions, issues or concerns that are voiced by the participant within 5-15 minutes.
Mindfulness Meditation and Phone CallsEach participant watches an mindfulness meditation introductory video in the initial session and then is asked to practice for 10 minutes each day using a guided audio, which includes a different topic each week. The time duration of the guided meditations increases to 15 minutes each day during Weeks 3-6. Each week for the six-week intervention, the researcher will contact the participant by phone at an agreed upon time and will discuss any questions, issues or concerns that are voiced by the participant within 5-15 minutes.
Weekly Phone Calls
Other
Each week for the six-week intervention, the researcher will contact the participant by phone at an agreed upon time and will discuss any questions, issues or concerns that are voiced by the participant within 5-15 minutes.
Meditation and Education and Phone CallsEach participant watches an mindfulness meditation introductory video in the initial session and then is asked to practice for 10 minutes each day using a guided audio, which includes a different topic each week. Participant receives 6 modules of AF education topics that are intended to be completed consecutively, one each week. The time duration of the guided meditations increases to 15 minutes each day during Weeks 3-6. Each week for the six-week intervention, the researcher will contact the participant by phone at an agreed upon time and will discuss any questions, issues or concerns that are voiced by the participant within 5-15 minutes.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Meditation
2018
Completed Phase 3
~4110

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline (initial), 12 month
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly baseline (initial), 12 month for reporting.

Who is running the study

Principal Investigator
P. W.
Prof. Paul Wang, Professor of Medicine
Stanford University

Closest Location

Stanford Health Care - Stanford, CA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 6 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Individuals with Symptomatic Paroxysmal Atrial Fibrillation
18 years old or greater
Able to read and understand English
Able to participate in weekly phone calls
Able to attend two video visit/phone sessions that are 6 weeks apart
A symptomatic episode of PAF within last 6 months

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What causes atrial fibrillation?

Add answer

Current treatment trends have largely maintained this pattern of care. Although many patient variables are identifiable, a precise definition of atrial fibrillation is complicated. This defines the current status of research in this area. New data continue to accumulate; many of the existing treatment strategies are not entirely clear-cut.

Unverified Answer

What is atrial fibrillation?

Add answer

Atrial fibrillation refers to an abnormality involving the electrical conduction system of the heart. It is common amongst people who do not have any other risk factors. A single beat of fowl-like flutter is characterised by a rapid regular beat at a rate of 100 times a second. The flutter pattern may change from left to right atrial (or possibly bilateral) atrium, or is consistent throughout the whole body.\n

Unverified Answer

Can atrial fibrillation be cured?

Add answer

Atrial fibrillation cannot be cured. The primary therapeutic strategy is to reduce and prevent its recurrence. Atrial fibrillation prevention is recommended. In the last decade, advances in treatment have reduced the proportion of patients in whom treatment is not adequate and those in whom it is not necessary.

Unverified Answer

How many people get atrial fibrillation a year in the United States?

Add answer

About 1,230,000 people will have a first episode of atrial fibrillation in 2019. Atrial fibrillation is a life-threatening problem among the younger population that needs to be carefully monitored.

Unverified Answer

What are common treatments for atrial fibrillation?

Add answer

Atrial flutter resolves within 10 days of initiation of antiarrhythmic therapy. Atrial fibrillation resolves within 24 hours of initiation of treatment with warfarin. Atrial flutter is most commonly cured with a course of antiarrhythmic therapy and prompt initiation of warfarin. Atrial fibrillation is most commonly cured with amiodarone. Atrial fibrillation persists when warfarin is inadequate, and typically resolves with antiarrhythmic therapy in conjunction with the correction of mechanical heart valve prosthesis thrombogenesis.

Unverified Answer

What are the signs of atrial fibrillation?

Add answer

A high-risk group for sudden cardiac death can be identified on the basis of the following: age ≥40, atrial fibrillation, previous atrial fibrillation, or left bundle arm block. There is no reliable method available to identify the initial fibrillation, and the best approach for prevention of sudden cardiac death in these high-risk patients remains unknown since a preventive strategy for this population has yet to be shown to be effective.

Unverified Answer

Have there been other clinical trials involving af education?

Add answer

In a recent study, findings have demonstrated that AF education is of benefit. However, it remains important that AF education and intervention be improved to be effective.

Unverified Answer

What does af education usually treat?

Add answer

Overall, this is a very valuable study with respect to AF education and it highlights the common misconception that 'AF education is a medication the same one as the “Cure” for atrial fibrillation', and for the most part it is not. For example, many of my patients come in very distressed by AF and it has long been known that a change in lifestyle is essential to the successful management and a cure of AF. There are many drugs that would fit the criteria of AF cure but they are not effective enough to be a valid cure. It’s not a cure but it has the potential to help in reducing the symptoms of AF such as fatigue and shortness of breath.

Unverified Answer

What is af education?

Add answer

While knowledge as only weakly correlated to compliance with the AF guidelines, it is clear that the education on anti-AF measures must be targeted to improve compliance with the rules.

Unverified Answer

What are the latest developments in af education for therapeutic use?

Add answer

In the present research, we provided an overview of the state-of-the-art knowledge of patients with atrial fibrillation following their education as a group or on an individual basis. A significant learning effect was demonstrated after the third educational intervention period in patients with atrial fibrillation undergoing cardioversion.

Unverified Answer

Does af education improve quality of life for those with atrial fibrillation?

Add answer

Af education has a significant impact on the quality of life of people with AF, and it appears that education, with particular emphasis on communication and lifestyle aspects, have less impact on patients' quality of life.

Unverified Answer

What are the common side effects of af education?

Add answer

Side effects of af education were not consistently reported in this survey. However, it is possible, given the wide range of ages interviewed, that some people experienced problems and problems which may not be reflected on the questionnaire. Furthermore, no side effects seemed to occur more frequently with AF education and counselling than with simple health information or placebo.

Unverified Answer
See if you qualify for this trial
Get access to this novel treatment for Atrial Fibrillation by sharing your contact details with the study coordinator.